Even less is known about the assembly of the neural net within
the mouse olfactory system, which, in the end, enables the individual to distinguish one smell from another with astonishing specificity and to remember such distinctions over time.
Somehow,
the mouse olfactory system had to evolve a way to adjust, to encode incoming sensory information so that it doesn't saturate the firing range of olfactory neurons.»
Not exact matches
The finding is based on the results of experiments that saw the connection between temporary elimination of
olfactory, smell
system, neurones in the noses of adult
mice, and weight loss.
The researchers scoured the already deciphered
mouse genome, looking for genes that might encode additional receptor proteins in its
olfactory system, the sensory cells that connect the nose to the brain.
Paying attention to the fact that each
olfactory sensory neuron (OSN) expresses an OR, Shun «ichi Kuroda, Professor and Nobuo Yoshimoto, Specially Appointed Associate Professor at the Department of Biomolecular Science and Reaction, The Institute of Scientific and Industrial Research, Osaka University in cooperation with Masato Suzuki, Chief Researcher, Advanced Research Division, Panasonic Corporation made a
system in which OSNs from
mice were applied to a microchamber array on a microscope slide and fluorescence was yielded when ORs responded to odorants.
Searching for an explanation to this alternate pheromone - detection
system, neuroscientists Stephen Liberles and Linda Buck of the Fred Hutchinson Cancer Research Center in Seattle scanned the
mouse olfactory epithelium for potential pheromone receptors.
Mark Albers uses the
olfactory system of
mice and humans to help understand the early events of neurodegeneration in order to find ways to intervene early in the disease process before symptoms appear and distinguish early pathologic events from changes produced by aging.
«This is the first study to examine
olfactory systems in adult
mice with regard to the potential to reverse the behavioral and neuroanatomical effects of emotional learning using extinction,» said Morrison.
We found widespread expression of Chd7 in early development of the
mouse in organs affected in CHARGE syndrome including eye,
olfactory epithelium, inner ear and vascular
system.
In the present study we have reported the transcriptional profile of the two main components of the
olfactory system in
mice, obtained by RNAseq and expression microarray.