Positive selection in the human genome inferred from human — chimp —
mouse orthologous gene alignments.
Positive selection in the human genome inferred from human — chimp —
mouse orthologous gene alignments Clark, A. G., S. Glanowski, R. Nielsen, P. Thomas et al. 2003.
Inferring nonneutral evolution from human - chimp -
mouse orthologous gene trios.
Not exact matches
This is only done for the antibodies corresponding to genes where the
mouse and human genes are
orthologous.
Using data from the National Center for Integrative Biomedical Informatics (NCIBI)'s MiMI: (Michigan Molecular Interactions) which contains data from IntAct, DIP, BIND and others, we identified conserved and predicted novel protein - protein interactions (interologs or interologues) in human,
mouse, fly, worm, and yeast based on interaction of
orthologous proteins found in the other organisms.
In the present study, we used a combination of BAC clone contig construction, polymorphism analysis of DNA from congenic strains, and sequence mining of the human
orthologous region to generate an integrated map of the Idd10 region on
mouse chromosome 3.
By contrast, Pou5f1 - null
mouse embryos maintained the expression of
orthologous genes, and blastocyst development was established, but maintenance was compromised.