Sentences with phrase «mouse pharmacokinetic»
We therefore performed a full mouse pharmacokinetic experiment.
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The physicochemical and mouse pharmacokinetic properties of BAZ2 - ICR were assessed.
Not exact matches
Corley also leads a $ 1.6 - million project that will be the first attempt to construct a physiologically based pharmacokinetic (PBPK) model for application to multiple species, including mouse and human.
Humphries - Bickley, T, Castillo - Pichardo, L, Corujo - Carro, F, Duconge, J, Hernandez - O'Farrill, E, Vlaar, C, Rodriguez - Orengo, J, Cubano, L, and Dharmawardhane, S. Pharmacokinetics of Rac Inhibitor EHop - 016 in Mice by Ultra-Performance Liquid Chromatography Tandem Mass Spectrometry.
Neuroprotective efficacy and pharmacokinetic behavior of novel anti-inflammatory para-phenyl substituted diindolylmethanes in a mouse model of Parkinson's disease.
The pharmacokinetic properties of J147 after a single dose of 20 mg / kg in mice show brain levels of about 600 nM at 2 h, over 10-fold above its EC50 in some cell culture neuroprotection assays [7], with a brain to blood ratio of approximately 0.5.
(A) The pharmacokinetic profile of J147 in mice was done by Pharmaron (Louisville, KY, USA).
Pharmacokinetic profile of J147 in mice.
We then explored pharmacokinetic properties of RIPK2 inhibitor 1 in the sera of mice.
Since the proposed model may be used in further studies and the results of the study could be interpreted by people who are not familiar with the peculiarity of nicotine / cotinine pharmacokinetics in mice, we attempted to estimate the level of nicotine (and e-liquid vapor) exposure used in the discussed study.