Sentences with phrase «mouse pharmacokinetic properties»
The physicochemical and mouse pharmacokinetic properties of BAZ2 - ICR were assessed.
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The pharmacokinetic properties of J147 after a single dose of 20 mg / kg in mice show brain levels of about 600 nM at 2 h, over 10-fold above its EC50 in some cell culture neuroprotection assays [7], with a brain to blood ratio of approximately 0.5.
We then explored pharmacokinetic properties of RIPK2 inhibitor 1 in the sera of mice.