Most studies of
mouse social hierarchy have focused on more aggressive behaviors such as how male mice might pick on new cage members, says Helmut Kessels, a neurologist at the Netherlands Institute for Neuroscience who was not involved with the research.
Not exact matches
To investigate the mPFC's role in
social ranking, Hailan Hu and her colleagues at the Institute of Neuroscience in Shanghai first worked out the
hierarchy within a group of
mice through challenges between pairs in tubes.
The crucial connections dictating a
mouse's place in the
social hierarchy appear to sit in the part of the brain called the medial prefrontal cortex (mPFC), responsible for emotion and decision - making.
But in mixed groups of mutated and genetically normal male
mice, there was no
social hierarchy.