But mouse studies don't always translate to humans.
The study was conducted in mice, and many findings from
mouse studies do not hold up in people.
While
the mouse study does not prove a direct connection between Zika infection and microcephaly, Rossi said, it does underscore the urgent need for effective animal models to further study the course of disease and its transmission.
Not exact matches
In a new
study based on
mice, scientists at Lancaster University found that a drug that goes after three diabetes - related targets «significantly reversed the memory deficit» in
mice who got the drug, as measured by their performance in a maze test when compared to
mice who didn't get the drug.
Findings from a 2010
study in the Journal of Nutrition demonstrated that blueberry - fed
mice had less atherosclerotic plaque than the
mice that
did not receive blueberry supplementation.
While curcumin has been shown to prevent depression, reverse liver damage, and prevent and treat Alzheimer's, my mom can go ahead and unarch that eyebrow — the majority of the
studies showing the dramatic results have only been
done on
mice and rats.
While
study results indicated that combining capsaicin with the chemicals «might promote cancer cell survival,» the report clearly stated that the control group of
mice treated only with capsaicin ``...
did not induce any skin tumors...» In addition, the
study repeatedly cited other research
studies in which the anti-cancer properties of capsaicin were solidly demonstrated.
A recent
study assessing the oncogenic potential of capsaicin revealed that dermal application of capsaicin
did not lead to the induction of preneoplastic or neoplastic skin lesions in the Tg.Ac
mouse model (47).
One
study looked at behavior among
mice, and concluded that males with new offspring develop new brain cells and neurons when they are physically present with their pups that
do not form when they are absent.
More work has to be
done on humans as many of the results showed up in
mice samples, however in
studying the human brains of women who had AD scientists found significantly less male fetal tissue in their brains as in the same of women who
did not have AD.
While our work has used
mouse models because we can
study the process in detail this way, we
do know that milk cells cross into human babies as well.»
The results of his
study done on cells and
mice were published this month in the journal Diabetes.
«There's nothing natural about what we're
doing, and adding a few tubes to a cage is not going to change that,» says Jonathan Godbout, a neuroscientist at The Ohio State University (OSU) in Columbus who
studies aging and stress in
mice.
Miho Sato and her colleagues at The Research Institute for Time
Studies at Yamaguchi University in Japan
did experiments in
mice and tissue cultures to show, for the first time, that increases in insulin affect circadian rhythms.
But a
study of
mice shows that breast cancer cells decamp in groups, and the clumps of cells have a better chance of establishing a colony than loners
do, Kevin Cheung of Johns Hopkins University reported December 7 at the annual meeting of the American Society for Cell Biology.
Carrying excess fat
does not contribute to a warmer body in obese
mice, a new
study on the insulating effects of fat finds.
Their
studies on
mice revealed that the treatment
did indeed reduce the swelling of the aorta and reduced levels of an enzyme that can break down the vascular wall and a protein involved in inflammatory processes.
In a 2010
study from Australia's University of New South Wales, feral cats were attracted to patches laced with a little Eau
du Mouse six days after the scent was placed.
He cautioned, however, that even the radiation - plus - CCL2 - blocking strategy explored in the new
study «doesn't cure the
mice — there's still more to be
done.»
In a
study published October 30 in Neuron, the scientists show that
mice genetically altered so they don't produce serotonin didn't scratch as much as normal
mice when exposed to irritants.
Wyss - Coray, whose group
did most of the
mouse studies that inspired the clinical trial, now plans to conduct a second, larger trial using plasma from which many proteins and other molecules have been removed.
«While this
study took place in
mice, the work sets the scene to
do early clinical trials in humans.
Mouse study suggests wirelessly controlled nanoparticles can provide a nonsurgical way to
do deep brain stimulation
The only previous demonstration — by researchers led by Shou - Wei Ding, PhD, a professor of Plant Pathology and Microbiology at UC Riverside and co-corresponding author of the current
study — was
done in embryonic stem cells and in newborn
mice.
But the Harvard stem cell and regenerative biologist Amy Wagers, a co-author on three of the
mouse papers, said in an email to STAT that she
does not agree that her teams»
studies provide a scientific basis for Maharaj's clinical trial.
Mice bred to have a malfunctioning form of CREB, Silva's
study demonstrated,
did not remember from one day to the next that they had already been taught to navigate a water maze or that they had previously been placed in a special cage where they received a mild electric shock.
Common ingredients in the cleaning sprays for your kitchen and bathroom make
mice less fertile, suggesting the compounds could
do the same to humans, according to a new
study.
The problems are many: Young blood didn't
do much for old
mice in other
studies.
And the trouble with extrapolating so much from
mouse studies is that «nobody has actually shown over the long term how long these quote un-quote improvements persist, and we don't know whether it's broadly improving aspects of aging or it's specific to certain tissues,» said Matt Kaeberlein, a biologist who
studies aging in dogs and other animal models at the University of Washington.
Gould and Georgiou say that their results don't necessarily invalidate previous
studies; they simply show that ketamine experiments in their lab work only when men inject the
mice.
Smoking
does plenty of bad stuff, but a new
study finds that cigarette smoke decreases the allergic response in
mice, anyway.
The UAB
study of the subunit H2A.Z in
mice was the first
done in a complex mammalian model.
In a new
study published online May 28 in the journal Cell Metabolism, Knutson and colleagues found that
mice lacking ZIP14 — when mated with
mice with hemochromatosis —
did not load iron in the liver.
He had no animal model of the infection to use in his
studies — rats and
mice are not susceptible — so he famously used an experimental subject that
did not require ethics approval or special funding: himself.
Interestingly, when compared to human cellular models,
mouse models of PD
did not demonstrate the same toxic cascade, according to the
study.
Now it seems like both the high and low levels could lead to depression: Yirmiya and his colleagues have
done studies in
mice for the past 20 years suggesting that a specific level of cytokines is needed to ward off symptoms of depression.
Gould's
study in
mice held another surprise: the metabolite that is active in
mice did not act through NMDA receptors.
The
study showed that
mice implanted with breast cancer cells lacking the protein developed small, self - contained tumors consisting of cells that didn't leave the tumor.
«Organ transplant rejection may not be permanent: Organ transplant rejection in previously tolerant hosts
does not lead to permanent immune memory,
mouse study shows.»
Such
studies couldn't really be
done in
mice, Diamond explained, because
mouse pregnancies only last 19 days.
Another tricky part of translating data from
mice to people is that unlike women who undergo C - sections, the
mice in this
study didn't receive antibiotics.
The off - target effects can be species - dependent, says Van der Stelt, which could explain why
studies in rats and
mice did not identify the drug's danger.
It doesn't take a neuroscientist to know that avoiding temptations from a drug - addled past is a good idea, so why go to all the trouble of
studying alcoholic
mice?
In the new
study, Datta and his team discovered that necklace neurons in
mice do not express GPCRs, unlike all other types of olfactory sensory neurons in mammals.
Differences and details A 2005
study of ethanol exposure in
mice did not find enhancement of synaptic plasticity.
When the researchers
did similar
studies in
mice with viral infections, they found the opposite effect.
Previous proteomic
studies in humans with brain injuries didn't control for the cause, while results in
mice examined the effects of time since injury or repeated injury, but not both.
The
study was
done with just one inbred line of
mice.
Mitchell's current analysis covered
studies involving a different
mouse model that
did allow for the observation of p - tau.
Mitchell's prior analysis examined lab
studies that used an Alzheimer's lab
mouse model that
did not allow for the
study of p - tau.