Not exact matches
In a new
study based on
mice, scientists
at Lancaster University found that a drug that goes after three diabetes - related targets «significantly reversed the memory deficit» in
mice who got the drug, as measured by their performance in a maze test when compared to
mice who didn't get the drug.
A
study at NYU Langone showed that when
mice were given oxytocin, they started caring for the other
mice's babies as if they were their own.
Some handy tools include ClickTale, which offers both
mouse - move and click heat maps and starts with a freemium plan where you can
study up to 400 page views a month, and CrazyEgg, which focuses mainly on heat mapping and starts
at $ 99 a month.
Sue, who works
at Memorial University, Newfoundland, Canada, first looked
at studies with
mice, which he suggests are «good models for human physiology.»
A
study at Harvard University found that alternate - day fasting among
mice, «protected
mice from strokes, Alzheimer's and Parkinson's disease, and consistently extended their life spans by 30 percent.»
Surprisingly, both the fiber additives and the supplements FAIL to feed your microbiome, and instead, they CANNIBALIZE the mucus lining for fuel,
at least for
mice, according to this
study.
A
study published in January found that the immune response to the common cold in a test group of
mice was impaired
at the lower body temperature compared to the core body temperature.
One
study looked
at behavior among
mice, and concluded that males with new offspring develop new brain cells and neurons when they are physically present with their pups that do not form when they are absent.
Not only would the new method, tested only in
mice, be more convenient but also more effective than the flu shot or nasal spray, according to a
study at the International Vaccine Institute in Seoul.
For example, Dr. Hugh S. Taylor, professor and chief of the Division of Reproductive Endocrinology and Infertility in the Department of Obstetrics, Gynecology & Reproductive Sciences
at Yale University,
studied the effects of non-ionizing radiation on the fetuses of pregnant
mice.
A 1999
study at Vermont's Anderson Laboratories concluded that two of three brands of disposable diapers tested emitted harmful chemicals capable of causing respiratory distress and pulmonary irritation in
mice.
One
study found brain hemorrhages in
mouse fetuses exposed to pulsed ultrasound
at doses similar to those used on human babies.
Mothers who overeat during the period when they are breastfeeding may have children who are
at increased risk of becoming obese and going through early puberty, a new
study of
mice suggests.
The authors of the
study referenced in the article found there was no causal connection between light and cell division in the brain of
mice if they had artificial light shined
at them
at one - hour intervals.
But a new
study shows that, in
mice at least, cosmic radiation likely causes cognitive impairment.
For this
study, researchers looked
at whether BNP played a role in transmitting acute, inflammatory or neuropathic pain in
mice.
«The newborn
mice inherited a very altered, skewed population of microbes,» said Eugene B. Chang, MD, Martin Boyer Professor of Medicine
at the University of Chicago, Director of the Microbiome Medicine Program of the Microbiome Center, and senior author of the
study, published this week in the journal Cell Reports.
A
study by researchers
at the University of Chicago Medicine shows that when
mice that are genetically susceptible to developing inflammatory bowel disease (IBD) were given antibiotics during late pregnancy and the early nursing period, their offspring were more likely to develop an inflammatory condition of the colon that resembles human IBD.
«In previous
studies, we found specific cells in the medial septum that fire
at higher rates when the
mouse moves faster.
«Our
study shows that epigenetic drift, which is characterized by gains and losses in DNA methylation in the genome over time, occurs more rapidly in
mice than in monkeys and more rapidly in monkeys than in humans,» explains Jean - Pierre Issa, MD, Director of the Fels Institute for Cancer Research
at LKSOM, and senior investigator on the new
study.
«This well - designed set of experiments shows that chronic THC pretreatment appears to restore a significant level of diminished cognitive performance in older
mice, while corroborating the opposite effect among young
mice,» wrote Susan Weiss, director of the Division of Extramural Research
at the National Institute on Drug Abuse, who was not involved in the
study, in an e-mail.
«The
mouse is a particularly suitable model in which to
study the development of the auditory system, because newborn
mice are deaf and only begin to perceive acoustic signals
at 12 days after birth.
On reanalysing data from the group's past
studies, such as on pain sensitivity to hot water, the researchers found that
mice tested by men showed lower baseline pain sensitivity than
mice tested by women.The work indirectly demonstrates potential effects on nearly any kind of medical research, says Joseph Garner, who
studies mouse behavior and well - being
at Stanford University in California.
In a
study published earlier this year, his team, along with scientists
at Arcturus Therapeutics, treated hemophilia in
mice using mRNA that encodes a clotting protein.
«Our research is the first to
study Zika infection in a
mouse model that transmits the virus in a way similar to humans,» explains Alysson R. Muotri, Ph.D., professor and director of the Stem Cell Program
at UC San Diego and co-senior author of the
study.
The new
study used the model to examine aggressive behavior directed
at unfamiliar
mice.
«Our research suggests that in
mice, males may be more vulnerable to the effects of maternal inflammation than females, and the impact may be life long,» says
study leader Irina Burd, M.D., Ph.D., an assistant professor of gynecology / obstetrics and neurology
at the Johns Hopkins University School of Medicine and director of the Integrated Research Center for Fetal Medicine.
A decade ago, Andrzej Bartke, a Polish - born physiologist
at Southern Illinois University (SIU) in Carbondale, was
studying reproductive endocrinology in giant
mice that had been engineered to overproduce human growth hormone.
They
studied the bone metabolism
at the cellular level using advanced imaging and computational techniques, which allowed them to identify 142 metabolites that were significantly altered by more than 1.5 times in the diabetic
mice.
Her main focus has been
studying how the central nervous system develops in embryos: in frogs as a graduate student, then in
mice as a postdoc
at Duke University starting in 1997, and later
at U.C. San Francisco when her lab moved to the Ernest Gallo Clinic and Research Center there in 1999.
Downstairs, the researchers maintained a colony of
mice at the other end of the size spectrum: the Ames dwarf line, which Bartke had been
studying since the»60s.
Ellen Heber - Katz, a scientist
at The Wistar Institute in Philadelphia, used to
study autoimmunity — that was until she noticed something strange in the
mice she was using to model lupus: The small holes that she had poked in their ears to distinguish the animals from one another kept closing.
Mice with colon cancer
studied by HQ Han and colleagues
at Amgen Research in California stopped eating, and lost 20 per cent of their body weight in three weeks.
«The implications for
mouse experiments are profound, and could help us cut through some persistent sources of confusion,» in genetic research, said Dr. Thaddeus Stappenbeck, an immunologist
at Washington University School of Medicine in St. Louis and a co-author of the new
study.
Marta Monteiro and colleagues
at the University of Lisbon, Portugal,
studied mice protected from the animal equivalent of multiple sclerosis by natural killer T - cells (NKT), a class of white blood cell which helps to control the immune system.
Most
studies of
mouse social hierarchy have focused on more aggressive behaviors such as how male
mice might pick on new cage members, says Helmut Kessels, a neurologist
at the Netherlands Institute for Neuroscience who was not involved with the research.
«Finding these similarities and
studying the aspects of
mouse biology that may reflect human biology, allows us to approach the
study of human illnesses in a better way,» affirms Bing Ren, one of the principal authors from the ENCODE Consortium and a lecturer in molecular and cellular medicine
at the University of California — San Diego.
«There's nothing natural about what we're doing, and adding a few tubes to a cage is not going to change that,» says Jonathan Godbout, a neuroscientist
at The Ohio State University (OSU) in Columbus who
studies aging and stress in
mice.
Researchers
studied the effect in
mice of consuming feed enriched with oil from glasshouse - grown genetically engineered Camelina sativa, developed
at the agricultural science centre Rothamsted Research.
The
study «provided the surprising result that one new therapy currently being explored to lower insulin resistance promotes, rather than decreases, the formation of bone in
mice,» says Darwin Prockop, a stem cell researcher
at Texas A&M College of Medicine in Temple, who was not involved in the work.
Based primarily
at Harvard with Maniatis, tenOever developed a knockout
mouse model to
study a particular protein, IKKε, that's involved in the immune response to viral infection.
They contacted Anutosh Chakraborty, a molecular biologist who was
studying such
mice down the hall
at Scripps
at the time.
Mouse study indicates signaling molecules
at play in cancer may also promote atherosclerosis
Géléoc and colleagues
at Boston Children's Hospital
studied mice with a mutation in Ush1c, the same mutation that causes Usher type 1c in humans.
In the current
study, Frank Longo, MD, PhD, and others
at Stanford University, tested LM22A - 4, a drug that specifically binds to and activates the BDNF receptor TrkB on nerve cells, in
mice that model the disorder.
A newly characterized group of pharmacological compounds block both the inflammation and nerve cell damage seen in
mouse models of multiple sclerosis, according to a
study conducted
at the Icahn School of Medicine
at Mount Sinai and published online this week in the journal Nature Neuroscience.
Mice transplanted with cells grown from a patient suffering from Huntington's disease (HD) develop the clinical features and brain pathology of that patient, suggests a
study published in the latest issue of Acta Neuropathologica by CHA University in Korea, in collaboration with researchers
at Université Laval in Québec City, Canada.
«
At room temperature, the
mice in our
study were unable to properly control the blood flow to their tails, which caused heat loss,» says Dr Jens Mittag, senior author on the paper.
An additional
study, currently available
at bioRxiv, led by the researchers from the CRG and Cold Spring Harbour Laboratory, highlights the fact that a substantial part of human and
mice genes have maintained an essentially constant expression throughout evolution, in tissues and various organs.
Senior author Madhav Dhodapkar, M.D., the Arthur H. and Isabel Bunker Professor of Medicine and Immunobiology, and chief of Hematology, said the
study, using tissue and blood samples from humans and
mice, shows that chronic stimulation of the immune system by lipids made in the context of inflammation underlies the origins of
at least a third of all myeloma cases.