Sentences with phrase «mouse study which»

This post shares the University of Wisconsin - Madison mouse study which found that the molecules produced by the microbiome (aka metabolites) tells our genes what to do (turn on or off).

Not exact matches

Some handy tools include ClickTale, which offers both mouse - move and click heat maps and starts with a freemium plan where you can study up to 400 page views a month, and CrazyEgg, which focuses mainly on heat mapping and starts at $ 99 a month.

They've conducted studies in mice, which showed that the device was able to improve the results of the drug by twelve times.

I was tired of books with stories about generals, parables about mice, and endless scientific studies with numbers that could point any which way.

In the study, mice were given food until they became obese, and were then fed the drug, which increases the cellular metabolism of obesity - linked white fat cells.

Sue, who works at Memorial University, Newfoundland, Canada, first looked at studies with mice, which he suggests are «good models for human physiology.»

While study results indicated that combining capsaicin with the chemicals «might promote cancer cell survival,» the report clearly stated that the control group of mice treated only with capsaicin ``... did not induce any skin tumors...» In addition, the study repeatedly cited other research studies in which the anti-cancer properties of capsaicin were solidly demonstrated.

As part of the study, researchers found that mice engineered to develop symptoms of human inflammatory disease, and which also lacked the ATG16L1 gene, developed gut damage.

«Our studies provide promising results in mice, which merit further investigation, such as adjusting the formulation, dose and delivery route of MAOA inhibitors, prior to ultimate clinical application.»

«Our study shows that epigenetic drift, which is characterized by gains and losses in DNA methylation in the genome over time, occurs more rapidly in mice than in monkeys and more rapidly in monkeys than in humans,» explains Jean - Pierre Issa, MD, Director of the Fels Institute for Cancer Research at LKSOM, and senior investigator on the new study.

In this study, they genetically engineered mice without CIB2, as well as mice in which a human CIB2 gene mutation had been inserted.

«The mouse is a particularly suitable model in which to study the development of the auditory system, because newborn mice are deaf and only begin to perceive acoustic signals at 12 days after birth.

McGlinn is now pursuing the same studies in mice, which is technically much more challenging.

The duo admits they have little evidence to back up their proposal, but they point to studies in their lab on mice, which were altered to be susceptible to both BSE and scrapie prion infection.

The study examined specific immune pathways known to be activated during flu infections in both humans and mice, which makes the findings relevant to children.

She latched onto the SCARB1 gene, inspired by a 2002 study in which MIT molecular biologist Monty Krieger found that mice engineered to lack that gene were more prone to heart attacks.

They studied the bone metabolism at the cellular level using advanced imaging and computational techniques, which allowed them to identify 142 metabolites that were significantly altered by more than 1.5 times in the diabetic mice.

Downstairs, the researchers maintained a colony of mice at the other end of the size spectrum: the Ames dwarf line, which Bartke had been studying since the»60s.

The study results were found using mouse embryonic stem cells, which are good cell models for the study of processes seen in human stem cells.

The research is part of a growing field called ecoimmunology, which aims to push the study of immunology beyond lab animals like fruit flies and mice and understand how immune systems function in real - world settings outside the lab.

«In our study, the hyperglycemic mice had increased bone resorption [the breakdown and absorption of old bone], which outpaced the formation of new bone.

Marta Monteiro and colleagues at the University of Lisbon, Portugal, studied mice protected from the animal equivalent of multiple sclerosis by natural killer T - cells (NKT), a class of white blood cell which helps to control the immune system.

This scheme mimics a human scenario better than the recent study, which analyzed mice that express or lack APOE from birth.

Dr. Schwarcz and his colleagues studied mice which were deficient in kynurenine 3 - monooxygenase, or KMO, an enzyme that is crucial for determining the levels of KYNA in the brain.

Three groups of middle - aged mice (about a year old) were studied: one group ate a normal diet, in which fewer than 30 percent of calories came from fat, while two others were fed high - calorie diets in which 60 percent of the calories came from fat.

A study published by Cell Press October 16th in Cell now reveals that gut microbes in mice and humans have circadian rhythms that are controlled by the biological clock of the host in which they reside.

It was known from previous studies that these mice have an overactive metabolism, caused by the energy needed to generate heat from brown fat, which might seem contradictory given their impaired thyroid hormone function.

Neurobiologist Gordon Fishell lost about 2,500 mice representing 40 genetic variants, which he had developed for studies of forebrain development over more than a decade.

Specifically, the Mount Sinai study was designed to test whether pharmacological compounds designed to block the function of XPO1 / CRM1 could stop disease progression in mouse models that exhibit some of the characteristics of MS. Researchers found that two chemical agents (called KPT - 276 and KPT - 350) prevented XPO1 / CRM1 from shuttling cargo out of the nucleus of nerve cells, which protected them from free radicals and structural damage.

The research team studied mice which had been fed with EPA oil from genetically engineered Camelina sativa, commonly known as false flax, but actually a member of the Brassicaceae family.

Because both of the new studies transplanted the entire community of gut bacteria from people into mice, they couldn't show which particular bugs played necessary or sufficient roles in MS.

«At room temperature, the mice in our study were unable to properly control the blood flow to their tails, which caused heat loss,» says Dr Jens Mittag, senior author on the paper.

If a lab is studying the impact of stress on the growth of new neurons, for example, and then it lets mice exercise on a running wheel — which has been shown to spark neuron growth — the study could be jeopardized, Godbout says.

Fiona Mathews of the University of Exeter, UK, who led the study, says the findings echo those in animals, which are also more likely to produce boys during times of plenty, whereas female mice with low blood sugar also seem more prone to producing girls.

Experiments with a compound called TNP [N2 -(m - Trifluorobenzyl), N6 -(p - nitrobenzyl) purine], which researchers often use to study obesity and diabetes, show that in mice the therapy can promote the formation of new bone.

A study published in tomorrow's Proceedings of the American Academy of Sciences describes how modified buckyballs — which soak up nerve - destroying chemicals — delay the onset of symptoms in mice suffering from Lou Gehrig's disease.

In the study, exosomes, which are generated by all cells and are naturally present in blood, were modified as «iExosomes,» capable of delivering small RNA to specifically target mutant KRAS, resulting in disease suppression and increased overall survival in mouse models.

«From other studies ***** we know that epigenetic modifications of the DPP4 gene, which are associated with an increased production of the enzyme, have a negative impact on the liver metabolism already in young mice, long before fatty liver disease emerges,» says Baumeier.

The study first examined how mice in which almost all beta cells were destroyed — similar to humans with type 1 diabetes — responded to injections of caerulein.

This mouse study shows that IL - 10 and IL - 27, which are secreted by B lymphocytes, regulate development of regulatory T lymphocytes.

The study compared intestinal wound healing in two groups of mice: 1) typical mice (wild type) found in nature and 2) mice genetically deficient in the healing factor IL - 10, specifically in macrophages, which impairs their ability to have normal wound repair.

The potential strategy — which targets metabolic pathways that are active only during intestinal inflammation — prevented or reduced inflammation in a mouse model of colitis while exerting no obvious effect in control animals with healthy, balanced bacterial populations, said Dr. Sebastian Winter, Assistant Professor of Microbiology and co-corresponding author of the study published online today in Nature.

In the first study, scientists transplanted fecal material from exercised and sedentary mice into the colons of sedentary germ - free mice, which had been raised in a sterile facility and had no microbiota of their own.

«Of mice and disease: Antibiotic - resistant bacteria discovered in NYC house mice: A study of mice collected from apartment buildings reveals they carry several disease - causing pathogens, some of which may be resistant to treatments.»

In the study, four groups of mice received different diets — two of which were supplemented with green tea or black tea extracts:

This was an experimental study in mice, which allows for conclusions to be made about cause and effect in this species.

Wyss - Coray, whose group did most of the mouse studies that inspired the clinical trial, now plans to conduct a second, larger trial using plasma from which many proteins and other molecules have been removed.

Studies in mice suggest that the answer may lie in the vagus nerve, which connects the brain to the abdomen.

For both studies, Schiestl and his team used mice that had mutations in a gene called ATM, which made them susceptible to a neurologic disorder called ataxia telangiectasia.

He cites one published study in which researchers compared the efficiency of an injected antibiotic with an orally administered agent, and with their combination, in treating tuberculosis - infected mice.