Sentences with phrase «mouse tibias»
(I and J) Representative x-ray and μCT reconstruction (I) and quantification of bone volume (BV) / total volume (TV) from μCT analysis of the mouse tibias (J).
http://stke.sciencemag.org/
(G and H) Representative x-ray and μCT reconstruction (G) of mouse tibias and quantification (H) of bone volume / total volume.
(E and F) Representative 3D μCT reconstruction of mouse tibias (E) and quantification (F) of bone volume / total volume from μCT analysis.
Not exact matches
«When implanted into the tibia or onto the skull of mice, moreover, we discovered that cells expressing miR - 940 can induce the kind of osteoblastic lesions that are typical of prostate cancer.»
Compared to normal mice with broken tibias, PlGF - deficient mice had fewer inflammatory cells at the wound and reduced blood vessel growth.
The researchers bred mice deficient for the protein — called placental growth factor (PlGF)-- and broke their tibias under anesthesia when they were 11 weeks old.
First, they drilled a 1 - millimeter hole into the tibia (in humans, the bone between the knee and the ankle) of anesthetized mice to simulate a bone break.
Bone marrow was collected from the femurs and tibias of sex - matched donor mice into HBSS.
Moreover, three - dimensional (3D) μCT reconstruction of the tibia revealed that mice injected with control cells had a significantly higher degree of osteolysis with a decreased ratio of bone volume to total volume compared to mice injected with ABL1 / ABL2 knockdown breast cancer cells (Fig. 4, E and F).
To directly examine whether ABL kinases play a role in regulating the colonization and survival of breast cancer cells in the bone microenvironment, we injected control or ABL1 / ABL2 knockdown breast cancer cells directly into the tibia of immunodeficient mice.
(A and B) Control or ABL1 / ABL2 knockdown 1833 cells (1 × 105) were injected directly into the tibias of the mice.
But surprisingly, Pierce said, examination of two major bones in the leg, the tibia and femur, in a living animal showed the receptor deficient mice actually had more marrow fat and lower bone mass.