Not exact matches
Researchers had focused so
much on
huntingtin's toxicity that it was surprising to discover this molecule has a regular day job, Cuervo notes.
And when they tracked the striatal neurons carrying the mutant
huntingtin over time, they found them
much more likely to die than those from other brain regions.
On the opening day of the biggest ever Huntington's disease therapeutics conference, we heard a lot about studying the complexities of the brain, and the role of the
huntingtin protein, still mysterious twenty years after its discovery - but not very
much about drugs.
The safety data may come first, but information about whether treatment with HTTRx lowered the level of
huntingtin protein in the spinal fluid — a
much - anticipated «biomarker» outcome — may take a little longer to materialise.
That's
much more dramatic than what happens in a
huntingtin - lowering treatment trial.