«This approach can complement the traditional
systemic chemotherapy,» Dr. Chiu explained.
«I don't see this protocol replacing
systemic chemotherapy altogether, but this method could be a helpful adjunct to the overall treatment plan.»
While radiotherapy can precisely target just the tumor site,
systemic chemotherapy spreads a wide net, sending drugs speeding throughout the entire body in an attempt to kill cancer cells while also killing many healthy cells.
About half of the patients (49 %) had received zero or one previous
systemic chemotherapy regimen.
Fibrolamellar hepatocellular carcinoma (FL - HCC) is a devastating cancer affecting children and young adults and currently does not have an effective
systemic chemotherapy.
Of the 29 patients, 24 had progressed after at least one round of
systemic chemotherapy.
It is comparing single - agent intralesional PV - 10 (every 4 weeks) vs
systemic chemotherapy (every 4 weeks) with investigator's choice of either DTIC or TMZ, in a 2:1 randomization.
Inflammatory breast cancer is generally treated first with
systemic chemotherapy to help shrink the tumor, then with surgery to remove the tumor, followed by radiation therapy.
The present standard of care for canine lymphoma consists of multiagent
systemic chemotherapy combinations.
Since 90 % of osteosarcomas will spread to the lungs, it is vital that
systemic chemotherapy is started immediately, even if there is no radiographic evidence of spread to the lungs.
Traditional treatments for osteosarcoma include amputation of the affected limb to address local pain issues, followed by
systemic chemotherapy for the treatment of distant metastasis.
Systemic chemotherapy involves the use of drugs that are given orally or by injection and then act throughout the body (systemic treatment).
Though the cause of infection is unknown, extensive resection of soft tissues, poor soft tissue coverage, use of orthopedic implants, and administration of local and
systemic chemotherapy are thought to be the contributing factors.
Because of this,
systemic chemotherapy is recommended as follow - up therapy for dogs with appendicular osteosarcoma.
Not exact matches
Attacking the perennial problem of
systemic toxicity from typical
chemotherapy treatments, Dartmouth investigators, led by Barjor Gimi, PhD, have engineered therapeutic cells encapsulated in nanoporous capsules to secrete antitumor molecules from within the tumor.
The device is ideal for those with GBM because it only acts on the brain and lacks
chemotherapy's
systemic side effects, says Eric Wong, a neuro - oncologist at Beth Israel Deaconess Medical Center in Boston, Massachusetts.
Dr. Chiu and his team have begun developing a more targeted method to deliver the
chemotherapy: «The ultimate goal is to create an alternative way to deliver
chemotherapy to people with neuroblastoma so we can increase the dosage of
chemotherapy but, at the same time, decrease the
systemic toxicity,» he says.
«
Systemic Candidiasis has been most noted in AIDS or cancer patients undergoing
chemotherapy in which the body's ability to defend itself from pathogens is compromised.
Malignant: none effective, may need to consider euthanasia;
systemic: poor response to
chemotherapy; cutaneous: corticosteroids, relapse is common, especially in Shar - Peis
Acupuncture and herbal therapy have been shown to be beneficial in many situations, including pain management, neuromuscular disease, asthma treatment,
chemotherapy side effects (nausea, anorexia), endocrine disease, and other
systemic disorders.
Below are some of the common specialty areas that we have experience with: - Infectious diseases: Tick - borne disease (Lyme disease, Ehrlichiosis, Rocky Mountain Spotted Fever, Bartonella),
systemic and local bacterial infections, feline and canine viral disease - Hematology: Immune - mediated hemolytic anemia, thrombocytopenia, leukemia, bone marrow diseases - Oncology: Surgical and
chemotherapy management, lymphoma, mast cell tumors, hemangiosarcoma, osteosarcoma, fibrosarcoma, mammary neoplasia, as well as benign and malignant skin masses such as adenomas and cysts - Urology: Kidney failure, bladder infections, stones / crystals, prostatic disease, pyelonephritis, FLUTD, protein - losing nephropathy, glomerulonephritis - Endocrine: Hormonal diseases such as hyper - and hypothyroidism, diabetes mellitus, cushings disease, addison's disease, endocrine skin disease - Gastroenterology: Chronic vomiting and / or diarrhea, inflammatory bowel disease (IBD), stomach ulcers / gastritis, colitis, pancreatic disorders, liver disease, protein - losing enteropathy - Respiratory disease: Feline asthma, canine chronic bronchitis, upper respiratory viral disease, pleural effusion, laryngeal paralysis - Cardiology: Heart murmurs and arrhythmias, heart failure, heartworm disease, hypertension - Ophthalmology: Gaucoma, cataracts, uveitis, corneal disease, ocular surgery - Allergic disease: Allergic dermatitis, food allergies, flea allergy, and allergic gastrointestinal and respiratory disease
Systemic anticancer
chemotherapy is the treatment of choice for canine lymphoma.
Chemotherapy uses
systemic medications that kill all fast - growing cells in the dog's body, including cells in dog tumours.