However, understanding the importance of the T cell response could help researchers prevent the development of
progressive multifocal leukoencephalopathy in autoimmune patients.
Dr. Hoffman recognized the similarity of these lesions to those known to occur in other breeds affected with
Canine Multifocal Retinopathy and he contacted OptiGen about the case.
These findings raise the possibility that viral shell mutations may influence the T cell response to John Cunningham polyomavirus in humans, and play a role in the development of progressive
multifocal leukoencephalopathy, the researchers wrote in the Journal of Virology.
Ophthalmoscopic changes are usually evident in affected dogs before the age of around 4 months and are characterized
by multifocal areas of retinal elevation that contain subretinal accumulation of serous fluid.
In the Spring of 2011, veterinary eye specialist, Dr. I. Hoffman, was surprised to observe
multifocal retinal lesions during a routine eye exam on a 13 month old Australian Shepherd.
Histopathologic examination of muscle biopsies revealed
multifocal areas of mixed mononuclear cell infiltration, myonecrosis and regeneration.
This is especially true
for multifocal prostate cancer, less aggressive tumors, and cases of prostatitis or prior prostate irradiation, where MRI alone may not give the correct localization and malignancy grade.»
«Reactive» Hepatitis: Diagnosed for unexplained liver enzyme activity; a term applied to liver biopsies lacking a distinct pattern but
showing multifocal lipogranulomas (small clusters of macrophages (white blood cells that take in foreign matter.)
Growth in the different glands is
usually multifocal in origin (meaning the tumors develop in many sites), rather than from spread or seeding of tumor cells from a single initial site.
Muscle biopsies
reveal multifocal necrosis, hypertrophy, atrophy, increased fibrosis and a variable increase in the number of fibers with internal nuclei and occasional whorled fibers.
Prasad notes, «This validated cutoff of 3.15 for SUVmax enables the diagnosis of prostate cancer with a high sensitivity and specificity in both unifocal and
multifocal disease.»
First two cases of severe
multifocal infections caused by Klebsiella pneumoniae in Switzerland: characterization of an atypical non-K1 / K2 - serotype strain causing liver abscess and endocarditis
Feeding activity by the blenny Excallias brevis
causes multifocal bleaching in corals: comment on Zvuloni et al..
, facial rubbing, air licking, fly catching, tail chasing, vocalization, pain reaction during atlantoxipital palpation., cervical myelopathy, fore leg paresis characterized by lower motor neurons,
multifocal CNS dysfunction, torticollis, scoliosis, seizure activity.
Switching to
multifocal glasses after cataract surgery may be the reason that cataract surgery did not decrease rates of falling as much as might be expected.
Long - term bacterial exposure can trigger nonsuppurative destructive cholangitis associated with
multifocal epithelial inflammation.
We previously reported the unusual case of a teenage girl stricken with
multifocal developmental dysfunctions whose physical development was dramatically delayed resulting in her appearing to be a toddler or at best a preschooler, even unto the occasion of her death at the age of 20 years.
We describe the first two
multifocal invasive infections due to Klebsiella pneumoniae recently observed in Switzerland.
Multifocal gastric carcinoid tumor in a patient with pernicious anemia receiving lansoprazole.
Neurological manifestations, including ataxia, epileptic seizures, dementia, migraine, neuropathy, myopathy and multifocal leucoencephalopathy
Lens height is essential for
multifocal prescriptions, such as Progressives, which require a minimum measurement of 28 - 30 mm.
Background Chronic non-infectious osteitis (CNO), also known as Chronic
Recurrent Multifocal Osteomyelitis, is a noninfectious inflammatory osteopathy predominantly affecting children and
Lysosomal storage diseases: a group of progressive
multifocal neurologic disorders caused by specific enzyme deficiencies leading to death of nerve cells and accumulation of their respective enzyme substrates in cells.
Multifocal immunologic damage to blood vessels probably results in ischemic damage to the skin and other susceptible organs.
Electrocardiography revealed sinus tachycardia — 156 bpm, with premature supraventricular and
multifocal ventricular complexes (fig 4).
Most of the patients with syringomyelia can live whole their lives with very mild symptoms within a normal life expectancies but some patients will have cervical myelopathy, cerebellovestibĂĽler dysfunction and
multifocal central nervous system dysfunction.
It can also occur in only a small area of the affected retina (focal detachment), in multiple but separate areas of the retina (
multifocal detachment) or across the entire affected retina (complete or total detachment).
Any English Springer Spaniel that
exhibits multifocal neurological signs, especially a dog descended from English families, should be tested for fucosidosis.
On the basis of Henry's signalment, history, and radiographic findings, his MRI results were most consistent with
multifocal discospondylitis and right - sided compression of the cauda equina secondary to extruded disc material, a cyst, or an abscess.
The gross appearance of skin lesions was as follows: focal or
multifocal alopecia (n = 17; 90 %)(Fig. 1), erythema (n = 15; 79 %), papulae (n = 11; 57.9 %), crusting (n = 5; 26.3 %) and lichenification (n = 2; 10.5 %).
Adjunctive HBOT in the Management of
Multifocal Traumatic CNS Lesions in a Canine A 5 - year - old male intact Boston Terrier was referred for adjunctive HBOT.
Yout, 45, contends that taking Tysabri to regulate her multiple sclerosis caused her to develop progressive
multifocal leukoencephalopath (PML), which is a rare brain infection.