Sentences with phrase «multifocal disease»
Prasad notes, «This validated cutoff of 3.15 for SUVmax enables the diagnosis of prostate cancer with a high sensitivity and specificity in both unifocal and multifocal disease.»
https://www.sciencedaily.com/ Not exact matches
Progressive multifocal leukoencephalopathy (PML) is a rare disease of the brain's white matter caused by the John Cunningham polyomavirus (JCV), a usually harmless virus that infects up to 80 percent of healthy adults.
Other eye diseases include, roughly in order of frequency, cataract, distichiasis, progressive rod - cone degeneration (a form of PRA), CEA, iris coloboma, persistent pupilary membrane, cone degeneration, and canine multifocal retinopathy.
The most common eye diseases in the breed are cataracts, distichiaisis, persistent pupilary membrane, and iris coloboma, with Progressive Rod Cone Degeneration (PRCD), a form of progressive retinal atrophy (PRA), Collie Eye Anomaly (CEA), Canine Multifocal Retinopathy (CMR), and glaucoma have been seen but are rare.
The phenotype of this disease is rather different from most known forms of PRA, with a multifocal rather than diffuse distribution of retinal degeneration.
Genes associated with the following forms of inherited canine retinal diseases were tested for association using fragment analysis in 11 PRA - affected and 11 unaffected Swedish vallhund dogs: canine multifocal retinopathy (cmr; gene: BEST1)[8], [9], rod - cone dysplasia type 1 (rcd1; PDE6B) and type 3 (rcd3; PDE6A)[23]--[26], progressive rod - cone degeneration (prcd; PRCD)[27], canine Leber congenital amaurosis (LCA; RPE65)[6], [7], cone - rod dystrophy (crdSWHD, NPHP4)[28], and achromatopsia / cone degeneration (ACHM / cd; CNGB3)[29], [30].
Based on our observations gathered during ophthalmic examination of affected dogs, we propose three clinical stages of disease ranging from diffuse multifocal red / brown discoloration of the tapetal fundus without associated visual deficits (Stage 1), to geographic retinal thinning / degeneration with mild to moderate signs of night - blindness (Stage 2), to more diffuse retinal thinning / degeneration affecting most of the tapetal fundus and associated with night - vision loss and severely impaired day - vision (Stage 3).
Progressive Multifocal Leukoencephalopath This is a white matter of the brain disease caused by a virus infection.