Sentences with phrase «multifocal leukoencephalopath»

Go the multifocal!!!

We perform diabetic eye examinations, cataract evaluation and surgery, multifocal and toric intraocular lenses, LASIK, eyelid surgery, advanced dry eye treatments, glaucoma and macular degeneration Frequency about 1 post per month.

Biogen Idec, Elan facing suits over MS drug side effects, The Boston Globe, September 10, 2013 NINDS Progressive Multifocal Leukoencephalopathy Information Page, National Institute of Neurological Disorders and Stroke

Progressive Multifocal Leukoencephalopath This is a white matter of the brain disease caused by a virus infection.

Yout, 45, contends that taking Tysabri to regulate her multiple sclerosis caused her to develop progressive multifocal leukoencephalopath (PML), which is a rare brain infection.

«My paintings are multifocal,» the British Op artist Bridget Riley once explained.

Instead, the exhibition is open - ended and «multifocal» — a tack that is, on the whole, disappointing.

Offer does not apply to the following ineligible items: Walgreens Ready Response, Dailies Total 1 30/90 pk, Dailies AquaComfort Plus Toric or Multifocal, Air Optix Colors, Bausch & Lomb ULTRA, pharmacy, photo, or gift cards.

Feeding activity by the blenny Excallias brevis causes multifocal bleaching in corals: comment on Zvuloni et al..

Unrelated to the herein described phenotype specific to Swedish vallhund retinopathy, we also observed focal and multifocal inactive chorioretinal scars in a number of dogs (n = 14).

Based on our observations gathered during ophthalmic examination of affected dogs, we propose three clinical stages of disease ranging from diffuse multifocal red / brown discoloration of the tapetal fundus without associated visual deficits (Stage 1), to geographic retinal thinning / degeneration with mild to moderate signs of night - blindness (Stage 2), to more diffuse retinal thinning / degeneration affecting most of the tapetal fundus and associated with night - vision loss and severely impaired day - vision (Stage 3).

The multifocal black spots in the tapetal fundus represent post-inflammatory scars.

Genes associated with the following forms of inherited canine retinal diseases were tested for association using fragment analysis in 11 PRA - affected and 11 unaffected Swedish vallhund dogs: canine multifocal retinopathy (cmr; gene: BEST1)[8], [9], rod - cone dysplasia type 1 (rcd1; PDE6B) and type 3 (rcd3; PDE6A)[23]--[26], progressive rod - cone degeneration (prcd; PRCD)[27], canine Leber congenital amaurosis (LCA; RPE65)[6], [7], cone - rod dystrophy (crdSWHD, NPHP4)[28], and achromatopsia / cone degeneration (ACHM / cd; CNGB3)[29], [30].

According to information provided by the dog owners, at least some of the Swedish vallhund dogs with MAC - like lesions suffered from severe gastrointestinal parasitism early in life which may have resulted in multifocal chorioretinitis.

Multifocal areas of esterase reactivity were identified, but it could not be determined from this reaction if staining correlated with localization of motor end - plates.

(G — I) In Stage 2, the retina showed signs of degeneration, indicated by multifocal, geographic thinning (arrow heads), beginning in the periphery and spreading throughout the tapetal fundus.

It is not unusual to see a thin halo of altered reflectivity or conus papillaris around the optic nerve head as seen in B and C. (D — F) Stage 1 is characterized by multifocal red or brown discoloration of the tapetal fundus (arrows).

Stage 1, the earliest stage with the mildest clinical signs, was characterized by a diffuse multifocal red or brown discoloration of the tapetal fundus (Fig. 2D — F).

The phenotype of this disease is rather different from most known forms of PRA, with a multifocal rather than diffuse distribution of retinal degeneration.

By examining 324 dogs of the Swedish vallhund breed in seven countries and across three continents, we were able to describe a new and unique form of PRA characterized by the multifocal appearance of red and brown discoloration of the tapetal fundus followed over time by thinning of the retina.

In Stage 2, the retina showed signs of degeneration, indicated by multifocal, geographic thinning, beginning in the periphery and spreading throughout the tapetal fundus (Fig. 2G — I).

Dr. Hoffman recognized the similarity of these lesions to those known to occur in other breeds affected with Canine Multifocal Retinopathy and he contacted OptiGen about the case.

In the Spring of 2011, veterinary eye specialist, Dr. I. Hoffman, was surprised to observe multifocal retinal lesions during a routine eye exam on a 13 month old Australian Shepherd.

Retinal elevations can remain static for several years, whereas multifocal outer retinal atrophy is often seen in older animals.

Focal and multifocal types manifest as linear folds and «rosettes» of tissue in the inner (sensory) retinal layer whereas in geographic forms there are larger areas of defective retinal development that appear as large irregular or horseshoe - shaped areas of mixed hyper - or hyporeflectivity in the central retina.

Histopathologic examination of muscle biopsies revealed multifocal areas of mixed mononuclear cell infiltration, myonecrosis and regeneration.

The gross appearance of skin lesions was as follows: focal or multifocal alopecia (n = 17; 90 %)(Fig. 1), erythema (n = 15; 79 %), papulae (n = 11; 57.9 %), crusting (n = 5; 26.3 %) and lichenification (n = 2; 10.5 %).

Multifocal lesions occur in 30 % to 40 % of cases.5

On the basis of Henry's signalment, history, and radiographic findings, his MRI results were most consistent with multifocal discospondylitis and right - sided compression of the cauda equina secondary to extruded disc material, a cyst, or an abscess.

Canine Multifocal Retinopathy (CMR)-- blister - like defects in the retina which can be detected by 4 months of age.

Muscle biopsies reveal multifocal necrosis, hypertrophy, atrophy, increased fibrosis and a variable increase in the number of fibers with internal nuclei and occasional whorled fibers.

Canine multifocal retinopathy, cone degeneration, corneal dystrophy, eyelid defects, hyaloid artery remnants, micropapilla, PHPV / PTVL, and uveodermatologic syndrome are occasionally seen in the breed.

The most common eye diseases in the breed are cataracts, distichiaisis, persistent pupilary membrane, and iris coloboma, with Progressive Rod Cone Degeneration (PRCD), a form of progressive retinal atrophy (PRA), Collie Eye Anomaly (CEA), Canine Multifocal Retinopathy (CMR), and glaucoma have been seen but are rare.

Other eye diseases include, roughly in order of frequency, cataract, distichiasis, progressive rod - cone degeneration (a form of PRA), CEA, iris coloboma, persistent pupilary membrane, cone degeneration, and canine multifocal retinopathy.

Moreover, many dogs develop multifocal TCC on the bladder.

It can also occur in only a small area of the affected retina (focal detachment), in multiple but separate areas of the retina (multifocal detachment) or across the entire affected retina (complete or total detachment).

«Reactive» Hepatitis: Diagnosed for unexplained liver enzyme activity; a term applied to liver biopsies lacking a distinct pattern but showing multifocal lipogranulomas (small clusters of macrophages (white blood cells that take in foreign matter.)

Most of the patients with syringomyelia can live whole their lives with very mild symptoms within a normal life expectancies but some patients will have cervical myelopathy, cerebellovestibüler dysfunction and multifocal central nervous system dysfunction.

, facial rubbing, air licking, fly catching, tail chasing, vocalization, pain reaction during atlantoxipital palpation., cervical myelopathy, fore leg paresis characterized by lower motor neurons, multifocal CNS dysfunction, torticollis, scoliosis, seizure activity.

Electrocardiography revealed sinus tachycardia — 156 bpm, with premature supraventricular and multifocal ventricular complexes (fig 4).

These include hip and elbow dysplasia, hypothyroidism, ear infections, diabetes, allergies, and a number of eye conditions such as progressive retinal atrophy (PRA) and multifocal retinal dysplasia (MRA).

Canine Multifocal Retinopathy (CMR) is an autosomal recessive eye disorder known to affect Great Pyrenees, English Mastiffs, Bullmastiffs, Australian Shepherds, Dogue de Bordeaux, English Bulldogs, American Bulldogs, Coton de Tulears, Perro de Presa Canario, and Cane Corsos.

Animal Genetics offers DNA testing for Canine Multifocal Retinopathy Types 1 and 2.

Tumor growth in different glands is usually multifocal, (meaning the tumors develop in many sites), rather than from spread or seeding of tumor cells from a single initial site.

Neurological manifestations, including ataxia, epileptic seizures, dementia, migraine, neuropathy, myopathy and multifocal leucoencephalopathy

Multifocal gastric carcinoid tumor in a patient with pernicious anemia receiving lansoprazole.

In a 2012 study, researchers reviewed the incidence of progressive multifocal leukoencephalopathy (PML) in clients detected with autoimmune rheumatic conditions (ARD) such as RA, lupus, or Sjögren's syndrome.

However, understanding the importance of the T cell response could help researchers prevent the development of progressive multifocal leukoencephalopathy in autoimmune patients.

In line with these data we demonstrate that combined deletion of Vhl and Pbrm1 in the mouse kidney is sufficient for the development of fully - penetrant, multifocal carcinomas, closely mimicking human ccRCC.

These findings raise the possibility that viral shell mutations may influence the T cell response to John Cunningham polyomavirus in humans, and play a role in the development of progressive multifocal leukoencephalopathy, the researchers wrote in the Journal of Virology.