Sentences with phrase «multifocal retinal»

In the Spring of 2011, veterinary eye specialist, Dr. I. Hoffman, was surprised to observe multifocal retinal lesions during a routine eye exam on a 13 month old Australian Shepherd.

These include hip and elbow dysplasia, hypothyroidism, ear infections, diabetes, allergies, and a number of eye conditions such as progressive retinal atrophy (PRA) and multifocal retinal dysplasia (MRA).

Not exact matches

The most common eye diseases in the breed are cataracts, distichiaisis, persistent pupilary membrane, and iris coloboma, with Progressive Rod Cone Degeneration (PRCD), a form of progressive retinal atrophy (PRA), Collie Eye Anomaly (CEA), Canine Multifocal Retinopathy (CMR), and glaucoma have been seen but are rare.

Focal and multifocal types manifest as linear folds and «rosettes» of tissue in the inner (sensory) retinal layer whereas in geographic forms there are larger areas of defective retinal development that appear as large irregular or horseshoe - shaped areas of mixed hyper - or hyporeflectivity in the central retina.

Retinal elevations can remain static for several years, whereas multifocal outer retinal atrophy is often seen in older aRetinal elevations can remain static for several years, whereas multifocal outer retinal atrophy is often seen in older aretinal atrophy is often seen in older animals.

The phenotype of this disease is rather different from most known forms of PRA, with a multifocal rather than diffuse distribution of retinal degeneration.

Genes associated with the following forms of inherited canine retinal diseases were tested for association using fragment analysis in 11 PRA - affected and 11 unaffected Swedish vallhund dogs: canine multifocal retinopathy (cmr; gene: BEST1)[8], [9], rod - cone dysplasia type 1 (rcd1; PDE6B) and type 3 (rcd3; PDE6A)[23]--[26], progressive rod - cone degeneration (prcd; PRCD)[27], canine Leber congenital amaurosis (LCA; RPE65)[6], [7], cone - rod dystrophy (crdSWHD, NPHP4)[28], and achromatopsia / cone degeneration (ACHM / cd; CNGB3)[29], [30].

Based on our observations gathered during ophthalmic examination of affected dogs, we propose three clinical stages of disease ranging from diffuse multifocal red / brown discoloration of the tapetal fundus without associated visual deficits (Stage 1), to geographic retinal thinning / degeneration with mild to moderate signs of night - blindness (Stage 2), to more diffuse retinal thinning / degeneration affecting most of the tapetal fundus and associated with night - vision loss and severely impaired day - vision (Stage 3).