Sentences with phrase «multiforme led»

Whereas, a phase I / II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme led to no significant improvement in overall survival, which could be due to inconsistent autophagy inhibition in patients treated with this regimen [29].

Not exact matches

A CAT scan and an MRI lead to a diagnosis more daunting than the first: glioblastoma multiforme, grade 4.

The results suggest the simultaneous activation of certain molecular pathways — actions among molecules in a cell that can lead to change — in particular the MAPK and PI3K cellular pathways, triggered tumor initiation and produced increasingly dense low - grade gliomas that quickly progressed to glioblastoma multiforme (GBM).

These preclinical studies have led to a clinical trial for patients with glioblastoma multiforme (www.clinicaltrials.gov NCT02046187).

Background ImmunoCellular Therapeutics is a California - based oncology firm with the lead candidate ICT - 107 entering Phase II for patients with a particular form of brain cancer, glioblastoma multiforme (GBM).