This guarded optimism is based on the phase I trial data showing an increase in overall survival of 4 - 6 months in 11 glioblastoma
multiforme patients (18 - 22 months) versus the 14 - 16 months survival typically seen with the standard treatment.
Not exact matches
In 2002 scientists showed that cytomegalovirus, or CMV, was active in the brain tumors but not the surrounding healthy tissue of all 27
patients they tested who had glioblastoma
multiforme.
For
patients with glioblastoma
multiforme, the vaccine did not seem to prevent the recurrence of cancer, so those
patients were offered follow - up chemotherapy.
The data suggests that the upregulation of MMP2 resulting from decreased Id4 expression in glioblastoma
multiforme (GBM) may contribute to the morbidity and mortality of GBM
patients.
Trial # 1: A phase I / II trial of HCQ in conjunction with radiation therapy and concurrent and adjuvant temozolomide in
patients with newly diagnosed glioblastoma
multiforme
This compares with 14 months for
patients with glioblastoma
multiforme — a complex and aggressive astrocytoma.
The median survival rate for
patients with glioblastoma
multiforme, or GBM, is a mere 14.2 months.
The researchers are currently enrolling
patients with stage 4 lung cancer and will soon begin enrolling people with glioblastoma
multiforme (brain cancer) in these phase II trials.
The cost per
patient above standard insurance billing for the phase II vitamin C glioblastoma
multiforme protocol is approximately $ 8000 spread over 9 months of test infusions.
Patients with recurrent glioblastoma multiforme (GBM) treated with an experimental vaccine made from the patient's own resected tumor tissue showed an improved survival compared with historical patients who received the standard of care alone, according to an analysis of a phase 2 trial of this vaccine that was recently published in the journal Neuro - Oncology and accompanied by an editorial highlighting the importance of th
Patients with recurrent glioblastoma
multiforme (GBM) treated with an experimental vaccine made from the
patient's own resected tumor tissue showed an improved survival compared with historical
patients who received the standard of care alone, according to an analysis of a phase 2 trial of this vaccine that was recently published in the journal Neuro - Oncology and accompanied by an editorial highlighting the importance of th
patients who received the standard of care alone, according to an analysis of a phase 2 trial of this vaccine that was recently published in the journal Neuro - Oncology and accompanied by an editorial highlighting the importance of the trial.
A phase I / II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in
patients with newly diagnosed glioblastoma
multiforme.
Whereas, a phase I / II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in
patients with newly diagnosed glioblastoma
multiforme led to no significant improvement in overall survival, which could be due to inconsistent autophagy inhibition in
patients treated with this regimen [29].
Glioblastoma
multiforme (GBM) is considered the most malignant of primary brain cancers with only about 12 % of
patients living beyond 36 months (long - term survivors).
These preclinical studies have led to a clinical trial for
patients with glioblastoma
multiforme (www.clinicaltrials.gov NCT02046187).
Background ImmunoCellular Therapeutics is a California - based oncology firm with the lead candidate ICT - 107 entering Phase II for
patients with a particular form of brain cancer, glioblastoma
multiforme (GBM).