«In principle, both these features make GA11 an attractive drug candidate to target glioma stem - like cells in glioblastoma
multiforme tumors,» said Ichiro Nakano, M.D., Ph.D., and colleagues in the paper.
Not exact matches
Glioblastoma
multiforme is the most common and deadliest of the glial
tumors because the cells reproduce so rapidly.
The
tumor is called a Glioblastoma
multiforme: also called The Terminator.
The investigators report that trapping virus - loaded stem cells in a gel and applying them to
tumors significantly improved survival in mice with glioblastoma
multiforme, the most common brain
tumor in human adults and also the most difficult to treat.
In 2002 scientists showed that cytomegalovirus, or CMV, was active in the brain
tumors but not the surrounding healthy tissue of all 27 patients they tested who had glioblastoma
multiforme.
In a study published in the Journal of NeuroOncology, TGen researchers report that PPF works to limit the spread of glioblastoma
multiforme, or GBM — the most common primary
tumor of the brain and central nervous system — by targeting a protein called TROY.
Researchers have identified a group of immune system genes that may play a role in how long people can live after developing a common type of brain cancer called glioblastoma
multiforme, a
tumor of the glial cells in the brain.
The loss of the
tumor suppressor gene PTEN has been linked to
tumor growth and chemotherapy resistance in the almost invariably lethal brain cancer glioblastoma
multiforme (GBM).
The results suggest the simultaneous activation of certain molecular pathways — actions among molecules in a cell that can lead to change — in particular the MAPK and PI3K cellular pathways, triggered
tumor initiation and produced increasingly dense low - grade gliomas that quickly progressed to glioblastoma
multiforme (GBM).
The
tumors studied fell into the broad category of high - grade gliomas: diffuse intrinsic pontine glioma, which strikes school - aged children; pediatric cortical glioblastoma, which affects primarily teens and young adults; anaplastic oligodendroglioma, which affects young adults; and glioblastoma
multiforme, which affects older adults.
Patients with recurrent glioblastoma
multiforme (GBM) treated with an experimental vaccine made from the patient's own resected
tumor tissue showed an improved survival compared with historical patients who received the standard of care alone, according to an analysis of a phase 2 trial of this vaccine that was recently published in the journal Neuro - Oncology and accompanied by an editorial highlighting the importance of the trial.
In addition to developing the new genetically engineered mouse model for the form of cancer called glioblastoma
multiforme, the researchers made a key discovery about brain
tumor biology via the mice.
My laboratory studies the biology of glioblastoma
multiforme (GBM), the most aggressive subtype of brain
tumors.
Glioblastoma
multiforme (GBM), an aggressive brain
tumor affecting both adults and children, has dismal outcomes as well:
LA JOLLA, CA — Scientists have long believed that glioblastoma
multiforme (GBM), the most aggressive type of primary brain
tumor, begins in glial cells that make up supportive tissue in the brain...
Glioblastoma
multiforme is the most common and aggressive primary brain
tumor and has one of the worst survival rates of all cancers.
He fought a very hard battle against his brain
tumor (glioblastoma
multiforme) and finally succumbed to the effects of the treatment.
Glioma - These
tumors arise from the supporting cells of the brain and include astrocytomas, oligodendrogliomas, glioblastoma
multiforme and ependymomas.