Neurona's founders have discovered that certain types of neuron transplants can rebalance nervous system activity, repair neural circuits, and rescue
multiple animal models of disease.
Not exact matches
His laboratory already has shown that by inhibiting calcium channels in T - cells, they were able to prevent T - cell activation in
animal models of autoimmune
diseases like
multiple sclerosis and colitis.
This
animal model closely resembles lesion kinetics as seen in human
disease [34] and use
of non-human primates allows for repetitive surgical sampling for
multiple time point analysis.
Katherine W. Klinger, PhD, Senior Vice President for Genetics and Genomics at the Genzyme Corporation, and Assistant Clinical Professor in the Department
of Pediatrics at the University
of Connecticut School
of Medicine suggested that for an orphan
disease it may be necessary to use
multiple animal models in the preclinical research stage, because one
animal model may not fully recapitulate the human
disease.
Animal gait is affected in
models of human disorders such as Parkinson's
Disease,
Multiple Sclerosis, Amyotrophic Lateral Sclerosis, spinal cord injury and many others.
Smith MR, Syed A, Lukacsovich T, Purcell J, Barbaro BA, Worthge SA, Wei SR, Pollio G, Magnoni L, Scali C, Massai L, Franceschini D, Camarri M, Gianfriddo M, Diodato E, Thomas R, Gokce O, Tabrizi SJ, Caricasole A, Landwehrmeyer B, Menalled L, Murphy C, Ramboz S, Luthi CR, Westerberg G, Marsh JL.A potent and selective Sirtuin 1 inhibitor alleviates pathology in
multiple animal and cell
models of Huntington's
disease..
Multiple studies show that the catechin compounds found in green tea can have various protecting effects on neurons in test tubes and
animals models, potentially lowering the risk
of disease like Alzheimer's and Parkinson's.