Sentences with phrase «multiple bone marrow»

Not exact matches

Multiple myeloma causes tumors to grow in the bone marrow, preventing the production of normal blood cells.

Bishop of Bradwell, Rt Rev John Wraw, has died after suffering multiple myeloma, which is a type of bone marrow cancer.

If desired, memorial contributions may be given to Multiple Sclerosis Society, Alzheimer's Assn. of Greater Chicago, or to the Claudia Garcia Bone Marrow Transplant Fund payable to Amiguitas de Claudia, Second Federal Savings, 3960 W. 26th St., Chicago, IL 60623.

He and his colleagues are now investigating how gene profiles are altered and whether these techniques could ease symptoms in people with high blood pressure, inflammatory bowel disease and multiple myeloma, a type of bone marrow cancer.

Using their new model, Jamieson, Crews and team found that two events converge to activate ADAR1 in multiple myeloma — a genetic abnormality and inflammatory cues from the surrounding bone marrow tissue.

Myeloma is often called multiple myeloma because it occurs at many sites within the bone marrow.

But in multiple myeloma, plasma cells grow out of control in the bone marrow, crowding out healthy cells.

«Taken together, these results support the hypothesis that multiple myeloma cells express bone - related genes in a Runx2 - dependent fashion that mimics bone marrow resident cells and likely contributes to tumor survival and growth in the bone microenvironment,» Yang and colleagues wrote in the paper.

Researchers have designed a nanoparticle - based therapy that is effective in treating mice with multiple myeloma, a cancer of immune cells in the bone marrow.

«We know multiple myeloma cells will anchor into bone marrow, and fat cells in the bone marrow will support the growth and spread of the cancer.

In humans, a comparison of bone marrow from 14 normal bone marrow donors, 35 multiple myeloma patients and 11 patients with a noncancerous condition called monoclonal gammopathy of undetermined significance (MGUS) showed that Runx2 levels were significantly higher in the multiple myeloma cells.

Researchers at Washington University School of Medicine in St. Louis have developed a nanotherapy that is effective in treating mice with multiple myeloma, a cancer of bone marrow immune cells.

Being overweight or obese has been known to increase the risk of multiple myeloma, a cancer of the plasma cells in the blood and bone marrow that develops more often after age 60.

And in 2010, a 46 - year - old woman developed multiple tumours in her kidney after having her own bone marrow stem cells injected at a private clinic in an attempt to treat her kidney failure.

Multiple myeloma is a cancer of plasma cells in the blood that causes tumor growths in bone marrow.

A new therapeutic approach tested by a team from Maisonneuve - Rosemont Hospital (CIUSSS - EST, Montreal) and the University of Montreal gives promising results for the treatment of multiple myeloma, a cancer of the bone marrow currently considered incurable with conventional chemotherapy and for which the average life expectancy is about 6 or 7 years.

Multiple myeloma is a cancer of the infection - fighting plasma cells, part of the immune system found mainly in bone marrow.

A personalized method for testing the effectiveness of drugs that treat multiple myeloma may predict quickly and more accurately the best treatments for individual patients with the bone marrow cancer.

inherited neurodegenerative disorders, an array of other genetic diseases, and multiple cancers of the bone marrow and lymph nodes.

«Despite current drugs and use of bone marrow transplantation, multiple myeloma is still incurable, and almost all patients eventually relapse,» says co-principal investigator and multiple myeloma specialist Craig Hofmeister, MD, MPH, assistant professor of medicine and a member of the OSUCCC — James Translational Therapeutics Program.

Obesity is accompanied by ectopic lipid deposition in multiple tissues, including the skeleton, where infiltration of adipocytes into the bone marrow niche may negatively impact bone formation (7, 8).

Modeling multiple myeloma - bone marrow interactions and response to drugs in a 3D surrogate microenvironment

Multiple myeloma preferentially localizes in the bone marrow where the majority of surrounding cells are represented by mature and immature neutrophils.

The diagnosis of multiple myeloma is made by the presence of elevated abnormal plasma cells in the bone marrow.

The only documented long - term complete remissions reported in multiple myeloma patients have occurred with allogeneic bone marrow transplantation, where a donor's blood stem cells (graft) are transplanted into the patient (host) with multiple myeloma.

No Place Like Home Rebecca Zoltoski was the first patient at the University of Chicago Medicine to undergo a blood and bone marrow stem cell transplant as an outpatient for her multiple myeloma.

Multiple myeloma cells are abnormal plasma cells (a type of white blood cell) that build up in the bone marrow and form tumors in many bones of the body.

Stem Cells Make Bone Marrow Cancer Resistant to Treatment Scientists at the Johns Hopkins Kimmel Cancer Center provided evidence that cancer stem cells for multiple myeloma share many properties with normal stem cells and have multiple ways of resisting chemotherapy and other treatments.

Elusive Cancer Stem Cell Identified Johns Hopkins Kimmel Cancer Center scientists have identified the cell likely to be responsible for the development of multiple myeloma, a cancer of the bone marrow that destroys bone tissue.

Malignant cancer cells or tumours can also accumulate outside the bone marrow, hence the term «multiple».

On a physiological level the immune system is composed of multiple cells, tissues, and organs including lymphocytes, leukocytes, bone marrow, the lymph nodes, the spleen, and the thymus.

Matt Damon's father has died at the age of 74 after a battle with multiple myeloma, a specific bone marrow cancer.

Kent had been battling multiple myeloma, a specific bone marrow cancer, since 2010 but his health had taken a turn for the worse lately.

Hence, disseminated histiocytic sarcoma is difficult to distinguish from MH, which is a multi-system, rapidly progressive disease in which there is simultaneous involvement of multiple organs such as spleen, lymph nodes, lung, bone marrow, skin and subcutis.

Multiple myeloma is a rare, malignant plasma cell cancer affecting the bone marrow and other blood producing organs.

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Diagnostic testing confirmed the diagnosis of multiple myeloma affecting her liver, spleen and bone marrow.

Lymphoid cancer in the chest, tonsil or bone marrow, blood or multiple organs often progress more rapidly than those only present in lymph nodes or a single organ.

Additional Cover for Critical Illness (optional)-- It provides an additional cover for ailments which includes Cancer of specified severity, Open Chest CABG, First Heart Attack of specified severity, Kidney Failure requiring regular dialysis, Major Organ / Bone Marrow Transplant, Multiple Sclerosis with Persisting Symptoms, Permanent Paralysis of Limbs, Stroke resulting in Permanent Symptoms.

The critical illnesses covered under the Standard Plan are as follows — cancer of a specified severity, stroke resulting in permanent symptoms, first heart attack of specified severity, open chest CABG, kidney failure requiring regular dialysis, Multiple Sclerosis with persisting symptoms, major organ / bone marrow transplant, permanent paralysis of limbs, surgery of aorta, primary pulmonary arterial hypertension.

Unless you have had a bone marrow transplant, an applicant diagnosed with multiple myeloma will typically be declined for life insurance.

Some of the common diseases covered are: • Cancer • First heart attack • Open heart replacement or repair of heart valves • Coma up to a certain severity • Major organ / bone marrow transplant • Motor neuron disease with permanent symptoms • Kidney failure • Stroke resulting in permanent symptoms • Permanent paralysis of limbs • Multiple sclerosis • Major burns • Loss of speech • End stage liver disease • Deafness • End - stage lung disease

A lump sum amount is payable for the first time diagnosis of any one of the 11 critical illnesses (First Heart Attack of specifiedseverity, Cancerofspecified severity, Stroke resulting in Permanent Symptoms, Open Chest CABG, Kidney Failure Requiring Regular Dialysis, Major Organ / Bone Marrow Transplant, Total Blindness, Coma of specified severity, Major Burns, Multiple Sclerosis with persisting symptoms, Permanent Paralysis of Limbs).

«He was diagnosed with multiple melanoma, which is cancer of the bone marrow.