Not exact matches
In recent years scientists have dramatically improved the power of EEG
by writing computer programs that compare recordings from
multiple locations around the head and then calculate which
regions of the
brain are producing the signals.
Such complexity is reflected
by the involvement of various
brain regions and
multiple pathways in the etiology of neurodegenerative diseases that render single drug target approaches ineffective.
By analyzing
multiple patients with damage to a particular voxel or cluster of voxels and comparing their cognitive abilities with those of patients in whom the same structures were intact, the researchers were able to identify
brain regions essential to specific cognitive functions, and those structures that contribute significantly to intelligence.
These mice were created and deposited
by The Pleiades Promoter Project (Centre for Molecular Medicine and Therapeutics, University of British Columbia); their goal is to generate 160 fully characterized, human DNA promoters of less than 4 kb (MiniPromoters) to drive gene expression in defined
brain regions of therapeutic interest for studying disorders such as Alzheimer's disease, Parkinson's disease, Huntington's disease, Amyotrophic Lateral Sclerosis (Lou Gehrig's disease),
Multiple Sclerosis, Spinocerebellar Ataxia, Depression, Autism, and Cancer.