The transmission of different states of gene expression through
multiple cell divisions and across generations has been termed «epigenetic,» since the underlying DNA sequence is identical in both states.
«That shows that the pattern of marks that was inherited is being transmitted through
multiple cell divisions.»
Rading, M. M. and Engel, T. A. and Lipowsky, R. and Valleriani, A. (2011) Stationary Size Distributions of Growing Cells with Binary and
Multiple Cell Division.
Not exact matches
In the clearest possible case, the ANT - OAR
cell would differ from a zygote on all of the parameters noted above: The ANT - OAR
cell would have a pattern of gene expression that is clearly distinct from a zygote; it would generate a homogeneous population of
cells rather than
multiple cell types; it would undergo simple cleavage
divisions and not produce any multicellular structures.
In humans, basal progenitors can undergo
multiple rounds of
cell division, thereby substantially increasing neuron number and ultimately the size of the neocortex.
Strikingly, sustaining Pax6 expression in mouse basal progenitors increased their capacity to undergo
multiple rounds of
cell division, as typically observed in primates.
Treatment for advanced melanoma has seen success with targeted therapies — drugs that interfere with
division and growth of cancer
cells by targeting key molecules — especially when
multiple drugs are used in combination.
To become a full - blown cancer (as opposed to a
cell with a single, potentially threatening mutation — a genetic risk factor for becoming a cancer) requires the accumulation of five to ten mutations, and statistically that requires
multiple rounds of
cell division and selection.
«Because technology now allows us to see the alternate pathways that cancer
cells use to drive growth, it will enable us to identify ways to cut off
multiple roads at the same time,» says James Heath, one of the paper's corresponding authors, at the NanoSystems Biology Cancer Center in the
Division of Chemistry and Chemical Engineering at the California Institute of Technology.
«ADRCs consist of
multiple cell types with
multiple potential benefits,» said Timothy D. Henry, MD, MSCAI, director,
division of cardiology at the Cedars - Sinai Heart Institute and the study's lead investigator.
The transit amplifying
cell undergoes
multiple rounds of symmetrical
divisions before all of its daughter
cells begin the process of differentiating into neurons.
She also investigates how asymmetric
cell division impacts on the cellular potential to give rise to
multiple lineages in vivo.
For instance, the laboratory has unraveled
multiple roles of survivin at
cell division, all of which ensure that the physical act of
cell division occurs properly.
«Our results show that macrophages and monocytes actively participate in the initiation and progression of
multiple sclerosis, which has long been considered a primarily T
cell driven disease,» says the study's senior author Catherine Hedrick, Ph. D., a professor in the
Division of Inflammation Biology.
These are anaplastic (undifferentiated
cell, characteristic of malignant neoplasms) round
cells that no longer resemble macrophages (white blood
cells within tissues, produced by the
division of monocytes) and display
multiple criteria for malignancy.
GM awarded two contracts for advanced development of battery packs, which require the integration of
multiple battery
cells, to Compact Power, Inc., a subsidiary of Korean battery manufacturer LG Chem, based in Troy, Mich.; and Frankfurt, Germany - based Continental Automotive Systems, a
division of Continental A.G., a tier one automotive supplier.