Sentences with phrase «multiple combinations with»

Designed to enrich a cat's play environment, the system's individual tunnels — in I, J and U shapes — easily connect to form multiple combinations with a variety of openings.

Not exact matches

«We remain committed to advancing our IDO pathway inhibitor indoximod, which continues to generate exciting data in combination with anti-PD-1 agents, cancer vaccines, and chemotherapy in multiple cancer types including melanoma, prostate cancer, acute myeloid leukemia, and pancreatic cancer.»
«We've seen this happen with other franchises like Call of Duty where multiple developers spur a great combination of both competition and collaboration.»
Empliciti will be used in combination with two other drugs to treat patients with multiple myeloma who have received one to three prior courses of medication.
The two companies plan to develop drugs to fight multiple cancer types, either alone or in combination with their other cancer treatments.
5) Context: The notion of context is endlessly complex, with each student, ministry site and learning group representing multiple combinations of contexts.
In this combination of two images with a multiple long exposure the interior of Salisbury Cathedral is illuminated by trails of candles carried by choristers during the annual «darkness to light» advent procession on December 1, 2012 in Salisbury, England.
Never struggle with multiple flour combinations again.
The company sees significant demand for similar combinations as some customers seek to differentiate their products not only through the novel delivery format, but also with premium positioning when featuring multiple healthy ingredients.
It also features a high - temperature short - time / ultra high - temperature line capable of multiple temperature / time combinations and upstream or downstream homogenisation with an in - line clean fill unit.
Sweet, tart, salty and refreshing, Kirsch Gose incorporates natural tart cherry juice with a classic German - style gose while Sour Monkey incorporates multiple fermentations via three different yeasts to create an exhilarating flavor combination.
Also, I still have some Santa Rita Hills Pinot Noir available with multiple Clone - Rootstock combinations if you're into that!!
Ever - more adventurous combinations with multiple layers and all sorts of toppings are being offered.
The storm had well and truly been weathered through a combination of excellent positioning and fight for the cause, with Christopher Schindler providing substantial evidence to that notion by being too strong for Okaka and Richarlison on multiple occasions.
The multiple color combinations ensure that it will fit in nicely with almost any nursery décor, which is especially great if you decide to change your nursery or use it in a different child's room.
The survey is 100 questions long with a combination of multiple choice and comment boxes.
The cost of multiple sitting fees with a photographer and the purchase of combination packages quickly adds up.
The first one avoids taking combination over-the-counter drugs which are those with multiple ingredients.
Combination vaccines: You can limit the number of jabs your baby receives by requesting combination vaccines, which protect your child against multiple diseases with a sCombination vaccines: You can limit the number of jabs your baby receives by requesting combination vaccines, which protect your child against multiple diseases with a scombination vaccines, which protect your child against multiple diseases with a single shot.
Compared with combination - fed infants, this enrichment approached statistical significance before correction for multiple comparisons.
The VISTA now allows for multiple combinations including, 2 MESA infant car seats, 2 bassinets or 2 toddler seats revolutionizing travel with twins and multiples.
A film which deserves multiple viewings, one of the aspects which stands out is the mad combination of seriously expensive and impressive special effects with a message so radical it's a surprise Hollywood allowed the film to be produced in the first place.
Principal investigator Cari Herrmann - Abell and her colleagues plan to expand on their previous efforts to develop multiple - choice test items by developing a set of constructed or open - ended response items that can be used in combination with the multiple - choice items to measure students» understanding of core disciplinary ideas, science practices, and crosscutting concepts — the three dimensions of science learning that are central to the vision of NGSS.
What has become clear from their research is that there is no single genetic pathway to controlling HIV; there likely are multiple routes, each with their own combination of genetic and environmental factors.
In a trio of studies to be presented at the 57th American Society of Hematology (ASH) Annual Meeting and Exposition in Orlando, investigators at Dana - Farber Cancer Institute will present the results of clinical trials showing that new drug combinations can significantly extend the time in which multiple myeloma is kept in check in patients with relapsed or treatment - resistant forms of the disease.
Many of the same people who usually earn spots with NASA (such as military test pilots) should still have an advantage in the new order, but the combination of multiple companies and flexible regulations may create opportunities for a broader group of would - be astronauts.
With multiple calendars, ancient Mesoamericans had a different combination of dates for every day, each combination having a special significance.
Clark and her co-authors identified four challenges to understanding and classifying mental disorders: what varied combinations of factors cause them, how to diagnose them given that they are not actually distinct categories, thresholds for diagnosis and other purposes such as treatment, and co-morbidity — the fact that most people with mental illness meet the diagnosis for multiple mental disorders.
The investigators add that predictive value might be even higher with combinations of multiple risk factors, rather than single predictors.
In testing multiple HDAC inhibitors in combination with the chemotherapy drug paclitaxel, known to give some benefit for this aggressive cancer, they found that class II HDAC inhibitors signal through a newly discovered pathway to promote synergy with chemotherapy treatment.
Treatment for advanced melanoma has seen success with targeted therapies — drugs that interfere with division and growth of cancer cells by targeting key molecules — especially when multiple drugs are used in combination.
Using multiple opsins as well as blue, yellow, and green light, he can experiment with various combinations of activation in hopes of eliminating symptoms of disease.
«In everyday situations we are frequently confronted with multiple talkers emitting auditory and visual speech cues, and the brain must decide whether or not to integrate a particular combination of voice and face.»
But that day will come, Steve Kay asserts, once researchers figure out the correct combination of drugs that work simultaneously on multiple triggers of eating and metabolism, just as hypertension is now routinely treated with two - or three - drug combinations.
The company in - licensed thalidomide in 1992 and received FDA approval to market the drug (as Thalomid) for treating severe cutaneous manifestations of leprosy in 1998 and for treating multiple myeloma in combination with dexamethasone in 2006.
One difficulty in studying the genetics of common mental illnesses is that they are generally caused by environmental factors in combination with multiple gene variants, any one of which usually could not by itself cause disease.
«Multiple myeloma patient study shows promise for natural killer cells: Phase I study included combination with high - dose chemotherapy and stem cell transplantation.»
The study is investigator led and has therefore focused on clinical need, targeting patients with progressive multiple sclerosis in whom most disability is incurred... The study also reports a predominant effect on neurodegenerative rather than inflammatory outcomes, suggesting a novel mechanism of action that might be suitable as combination treatment with immunomodulatory treatments... Further phase 3 studies to measure the effect of simvastatin on sustained disability, particularly in patients with non-relapsing secondary progressive and primary progressive multiple sclerosis, are clearly needed, but this trial represents a promising point from which to develop trials of progressive disease.»
The queen bee, who, in the course of their mating flight, mate with different drones multiple times, passes on to fertilized eggs a random combinations of two csd copies, so - called alleles.
Previous studies have not looked at pre-existing signs of damage nor considered analysing multiple signs in combination, yet having multiple and old signs are both very common in patients with stroke.»
After much experimentation with multiple combinations, the researchers found that adding two more signals to the mix — transcription factors called ISL1 and LHX3 — turned the skin cells into spinal cord motor neurons in about 30 days.
This system could be used in combination with hundreds of existing mouse strains that have been engineered to express known cancer genes, allowing researchers to study more thoroughly the interactions of multiple genes.
Kessler will conduct a study of a combination therapy using dalfampridine — a drug recently approved to improve walking in patients with multiple sclerosis — with a standardized program of locomotor training, a rehabilitative intervention that has improved walking and other functional outcomes in persons with spinal cord injuries.
Combination therapies often include multiple types of chemotherapy or chemotherapy combined with other treatment options.
iTeos is now developing EOS200271 which is a synthetic, small molecule inhibitor of indoleamine 2,3 - dioxygenase (IDO1), which has demonstrated the same anti-tumour activity in multiple preclinical tumour models in combination with immune checkpoint inhibitors as competitors, but also has demonstrated superior brain penetration.
Plerixafor has been approved by the FDA as the first small - molecule CXCR4 antagonist for use in combination with granulocyte - colony stimulating factor (GCSF) to mobilize hematopoietic stem cells to the bloodstream for collection and subsequent autologous transplantation in patients with non-Hodgkin's lymphoma and multiple myeloma.
Researchers at the University of California - San Francisco's Multiple Sclerosis Research Group conducted one of the most comprehensive examinations to date of the genome, and even part of the epigenome, of a set of identical twins, only one of whom had been stricken with MS. Scientists are sure MS is caused by some combination of genetic susceptibility and external trigger.
Preliminary findings presented at ASH suggest a «favorable emerging clinical profile» for once weekly administration of MLN9708 in combination with lenalidomide and dexamethasone in patients with newly diagnosed multiple myeloma.
Examining all the combinations of smoking status of parents and grandparents with the gender of the children and four different traits is quite likely to generate a chance finding of borderline significance, especially when using a series of different adjustments and not adjusting for multiple comparisons.
Plerixafor in combination with granulocyte - colony stimulating factor (G - CSF) has been approved for hematopoietic stem cell mobilization to the peripheral blood in patients with non-Hodgkin's lymphoma and multiple myeloma [54].
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