Sentences with phrase «multiple cycles in»

While discounts are available for multiple cycles in the same year, patients must reapply for discounts each year.

Not exact matches

«But as 2018 unfolds and signs of the cycle stalling start to build, watch for relative outperformance from defensives as the multiples in Health Care, Staples, Utilities, and REITs fall by less than the market.»

«A smoother iPhone cycle (no boom - bust) should drive increased stability in earnings, commanding a higher multiple.»

Similarly, looking at it from an enterprise value basis, assuming a free cash flow margin of 25 % for FY18 (consensus estimates are at 24 %) on sales growth of 12 % (in - line with consensus) along with a EV / FCF multiple of 11x (in - line with the peak multiple leading up to the iPhone 6 cycle), we come up with a stock value in the mid $ 160s as well.

Well... just imagine a bar crawl, you know one of those popular activities that friends do when they drink at multiple bars all in a single night, typically traveling by foot, bus, maybe even cycle?

«Grief can express itself in so many ways and cycle through multiple points during the day: shock, denial, anger, blame, sadness.

By having multiple products that flourish in different economic cycles, brokers can have other profit avenues to concentrate on or substitute in times when commercial mortgages are going through a slow period.

The S&P 500 registered a record high after an advancing half - cycle since 2009 that is historically long - in - the - tooth and already exceeds the valuation peaks set at every cyclical extreme in history but 2000 on the S&P 500 (across all stocks, current median price / earnings, price / revenue and enterprise value / EBITDA multiples already exceed the 2000 extreme).

As we saw in multiple early selloffs and recoveries near the 2007, 2000, and 1929 bull market peaks (the only peaks that rival the present one), the «buy the dip» mentality can introduce periodic recovery attempts even in markets that are quite precarious from a full cycle perspective.

The report cites «multiple examples of complacency throughout CBA [which] could be described as a repetitive cycle of inertia» and said «one of the main drivers of the inconsistent influence of the risk function has been the amount of bureaucracy built up in CBA, resulting in risk management being perceived as a low priority «administrative task».»

Once rock - solid corporate balance sheets have weakened of late as debt as a percentage of assets and debt as a multiple of available cash flow have both risen to levels last seen before the peak of the US housing cycle in 2007.

«True managers need to be tested in multiple business cycles to prove their compound annual return is consistent over long periods of time» Thomas Kahn

First, it's great for investors to have an idea of what «multiple range» a company has traded at in the past — there's a lot of value to this, and most relevant for cyclical firms (mainly industrials) that may, from a fundamental standpoint, exhibit similar (but not identical) patterns with respect to both earnings and their PE through the course of each economy cycle: think Boeing (BA) and the commercial aerospace cycle; Ford (F) and consumer demand for auto sales; or United Continental (UAL) with respect to premium air travel demand.

Perhaps there is some endless cycle in which singularities coalesce and expand within multiple planes of existence.

That would be a red flag to anyone with a sense of sanity) 5) Being a convicted con — it makes sane sense that this convicted con - artist also had a thing for young girls and multiple wives (how convienient if one is in a monthly cycle, chances are he could get the boo - ty from another — and keeping them below legal age is an added treat for a pedophile - oriented putz) 6) I'm still stuck on the multiple boo - ty thing... was a great thing in my younger days but I grew into self - reponsibility to my mate and offspring 7) I'm still stuck on the Black thing in Mormonisim — banned until recent time.

I've presoaked in SHOUT overnight, I've run hot cycles with just vinegar, multiple rinses and soaks...... I'm going to try Dawn dish soap to soak them in next and maybe some essential oils that are suppose to help cut the «grease» maybe if it's oily protein stuff hanging on to the fabric ~ I also read that it could be fungus forming and eating at the oily fats??? I really hope that's not the case ~ I kept thinking I can NOT be the only one with this problem ~ I just wish I knew how to resolve it!!!!

Our proprietary food safety processes — unmatched in the industry — involve multiple interventions and test points throughout the production cycle.

Treatment of APL requires cycles of multiple therapeutic agents, including chemotherapy, in three distinct phases: induction, consolidation, and maintenance.

Rearfoot and Forefoot Gel ® technology cushioning systems: Attenuates shock during impact and toe - off phases, and allows movement in multiple planes as the foot transitions through the gait cycle

If that was not enough the cycling legend has multiple road and track world medals to his named was the first British man to win the Tour de France in 2012.

Joey Bunz Premium Hemp Inserts have a combination of hemp / cotton to ensure the inserts will retain their shape through multiple wash and dry cycles and subsequent children in your family.

What this suggests is that genetics somehow play a role in multiple ovulation (also known as hyperovulation), in which more than one egg is released during a menstrual cycle.

For instance, the fertility drug Clomid (clomiphene) works by stimulating ovulation and sometimes cause the release of multiple eggs in a single cycle (referred to as superovulation).

As they get older, their cycle will grow in multiples of 90 - staying awake for 3 hrs, then 4.5 etc. until they are around 1 year and begin to follow the clock (ie set naps at the same time each day).

Human multiple births can occur either naturally (the woman ovulates multiple eggs or the fertilized egg splits into two) or as the result of infertility treatments such as IVF (several embryos are often transferred to compensate for lower quality) or fertility drugs (which can cause multiple eggs to mature in one ovulatory cycle).

BabyKicks Joey Bunz Hemp Inserts have a combination of hemp / cotton to ensure the inserts will retain their shape through multiple wash and dry cycles and subsequent children in your family.

Multiple chambers elected by different electoral systems at different times in the electoral cycle would provide such safeguards, as I have outlined before.

As President, Obama has turned these ideas into the theme, «Nation building at home», a concept he referred to multiple times in the 2012 election cycle.

While most nonprofit groups operate in multiple races, in part to demonstrate to the I.R.S. that they are not overly attached to individual candidates, several have emerged this cycle with what appears to be the sole purpose of supporting a single candidate.

Unlike in 2008, when those events were largely viewed only on televisions, voters this cycle were increasingly likely to watch on multiple screens.

Cuomo has noted the cost of calling for special elections in the middle of a cycle and has often waited for the general election cycle or multiple vacancies to set a date in order to alleviate the amount spent by the Board of Elections.

«In 2014 Hanna won the Independence Party's nomination (New York allows candidates to accept multiple parties» nominations) and if he does the same thing this cycle, he'll have a spot on the general election ballot.

But because genes can regulate multiple processes, more work is needed to determine the safety of modifying the cell cycle in such a way.

The ancestral flower was bisexual with multiple whorls (concentric cycles) of petal - like organs, in sets of threes.

Multiple eggs are stimulated to develop at once (as opposed to just one egg in a natural ovulatory cycle).

The new study revealed the Ebola VP40 protein assumes different structures to perform multiple roles in the virus's life cycle — membrane trafficking, virus assembly and control of replication.

Now, using two deep cores collected at two Ocean Drilling Program sites in the Southern Ocean, Jaccard and colleagues have reconstructed ocean records of productivity and vertical overturning reaching back a million years, through multiple glacial - interglacial cycles.

The next step for Russell and his colleagues is to see if this pattern is repeated in multiple glacial cycles.

«Our next step is to perform a health - economic analysis to show that the reduction in multiple pregnancy rates results does indeed result in a financial benefit for the government, so that the refunding of six cycles is still a responsible policy,» said Professor Thomas D'Hooghe, last author of the paper and head of the Leuven University Fertility Center.

The practice of freezing embryos and then thawing them and transferring them to women's wombs (known as frozen embryo transfer or FET) also increased by 27.6 % between 2008 and 2010; FET cycles had approximately half the multiple birth rate when compared with fresh embryo transfers, namely 13 % (2008), 11.9 % (2009) and 12 % (2010), with just 0.6 % triplet births in all three years.

«In modern biology mitochondria are considered to be much more than the powerhouse of the cell; they integrate multiple intracellular signals to regulate progression through the cell cycle and into apoptosis.

This study, which will be published Oct. 24 in eLife, and two other new Northwestern studies in Oncotarget and Cell Cycle by the Peter group, describe the discovery of the assassin molecules present in multiple human genes and their powerful effect on cancer in mice.

His team discovered these special sequences are distributed throughout the human genome, embedded in multiple genes as shown in the study in Cell Cycle.

Also this technique is only likely to be useful in a small proportion of cycles in which embryos are cultured to the blastocyst stage and multiple embryos are then available for selection.

GE & Caithness Announce Innovative Power Deal that Could Exceed $ 1B to Build Multiple HA Combined - Cycle Power Plants in US

During the first application cycle (September 2015 — April 2016) Takeda and Consortium investigators completed a process for soliciting, prioritizing and co-developing research proposals resulting in the recent funding of multiple projects.

Close - to - natural growth conditions (e.g. upright position, roots in liquid and leaves in air, maintenance of a 16 hrs / 8 hrs diurnal cycle) are essential for observations lasting multiple days.

It supports researchers at national laboratories, universities and research institutes focused on developing and testing the next generation of adsorbents that will exhibit higher adsorbent capacity, faster binding and lower degradation over multiple use cycles in seawater.

This is in accordance with previous reports that decitabine and 5 - azacytidine produce a marked synergistic effect in combination with suberoylanilide hydroxamic acid and romidepsin in T - lymphoma cell lines by modulating cell cycle arrest and apoptosis.26, 27 As a mechanism of action, KMT2D mutations of B - lymphoma cells promote malignant outgrowth by perturbing methylation of H3K4 that affect the JAK - STAT, Toll - like receptor, or B - cell receptor pathway.28, 29 Here our study indicated that dual treatment with chidamide and decitabine enhanced the interaction of KMT2D with the transcription factor PU.1, thereby inactivating the H3K4me - associated signaling pathway MAPK, which is constitutively activated in T - cell lymphoma.13, 30,31 The transcription factor PU.1 is involved in the development of all hematopoietic lineages32 and regulates lymphoid cell growth and transformation.33 Aberrant PU.1 expression promotes acute myeloid leukemia and is related to the pathogenesis of multiple myeloma via the MAPK pathway.34, 35 On the other hand, PU.1 is also shown to interact with chromatin remodeler and DNA methyltransferease to control hematopoiesis and suppress leukemia.36 Our data thus suggested that the combined action of chidamide and decitabine may interfere with the differentiation and / or viability of PTCL - NOS through a PU.1 - dependent gene expression program.

Writing in The BMJ today, researchers describe a new calculator that has been developed to estimate the individualised chances of couples having a baby, both before and after first IVF treatment, and over multiple cycles.