Sentences with phrase «multiple different cancer»
The authors showed that the use of this drug remains widespread in Asia and particularly in Taiwan, and that it appears to increase the risk of multiple different cancer types.
http://stm.sciencemag.org/ Not exact matches
But the five companies that the state selected in 2015 to get marijuana into the hands of people suffering from debilitating and sometimes terminal diseases such as cancer, AIDS and multiple sclerosis tell a different story.
«This could be useful in developing new combination therapies, where multiple drugs are used simultaneously to treat a cancer by attacking different parts of the cancer cells at the same time.»
That trend is problematic considering that African - Americans — the most at - risk population for multiple myeloma — have different genetics that can affect how this type of cancer progresses and what kind of targeted therapies are most effective, said Zarko Manojlovic, lead author of the study.
«Our data confirmed that, while the rate of growth of triple - negative breast cancer was not affected by CDK 4/6 inhibitors, this class of drugs was able to significantly inhibit the spread of triple - negative breast cancer to distant organs when tested in multiple different triple - negative breast cancer models, including patient - derived xenografts.»
If metastatic cancers are most often made up of cells with different genetic drivers, perhaps researchers should be targeting the primary tumor with multiple drugs to contain the cancer.
To understand this spread, the Penn researchers developed a mouse model that uses multiple fluorescent proteins to tag and track different pancreatic cancer cells as they enter the bloodstream and spread to distant organs.
The researchers then compared tumor cells isolated from multiple different breast cancer patients and found that cells expressing lower amounts of Numb - 1 and -2 were more resistant to the chemotherapy agent cisplatin.
The resulting «map» of gene - drug interactions allowed the researchers to accurately predict the responses of multiple human cancer cell lines to different chemotherapy agents based on the cell lines» genetic profiles and also revealed new genetic factors that appear to determine the response of breast and ovarian tumor cells to common classes of chemotherapy treatment.
Both Tsigelny and Kurzrock agreed that this finding is an excellent example of the power of collaboration between SDSC and the Moores Cancer Center, and that such modeling needed to be studied across tumors and with multiple different genes involved in cCancer Center, and that such modeling needed to be studied across tumors and with multiple different genes involved in cancercancer.
«Having these personalized laboratory models, which we can make in a matter of weeks, will let us test multiple different drugs on the tumor and help us bring precision medicine to individuals with bladder cancer.»
A multiple myeloma patient whose cancer had stopped responding after nine different treatment regimens experienced a complete remission after receiving an investigational personalized cellular therapy known as CTL019 developed by a team at the University of Pennsylvania.
«Cimetidine is one of the most interesting examples of repurposed drugs in oncology — a drug with an extensive history of pre-clinical and clinical evidence of efficacy in a range of different cancers and with multiple mechanisms of action at work,» says Pantziarka.
Hsp90 inhibitors are among several innovative new types of treatment designed to attack cancer indirectly, by destabilising multiple different proteins required for the growth and survival of cancer cells.
Different cancers are a result of multiple genetic mutations.
Dr. Mucke expects that an effective Alzheimer's solution will include multiple therapies to address the numerous proteins implicated in the disease — including amyloid - beta, apoE4 and tau — in much the same way that hypertension, cancer and severe infections often require treatment with combinations of different remedies.
Willet, Mills, and their colleagues believe the discovery that cells in different organs go through the same process to become proliferative could lead to new potential targets for cancer treatment because the factors that initiate tumours could be the same in multiple organs.
Ultimately, Dr. Mucke expects that the effective prevention and treatment of Alzheimer's will have to include multiple therapeutic strategies — in much the same way as hypertension or cancer often require the combination of different treatments.
As with cancers and infectious illnesses, mental illnesses once lumped together as a single disorder are beginning to be understood as multiple illnesses or subtypes that may stem from different causes and require different treatments.
Several checkpoint inhibitors, targeting multiple different checkpoints, are currently enrolling breast cancer patients:
In addition, because ZVex product candidates have the potential to carry the genetic material of different tumor antigens, as well as immunostimulatory molecules, we can design them to target multiple types of cancers.
PHILADELPHIA — A multiple myeloma patient whose cancer had stopped responding after nine different treatment regimens experienced a complete remission after receiving an investigational personalized cellular therapy known as CTL019 developed by a team at the University of Pennsylvania.
Vitamin D has had a positive effect on many different diseases, including multiple sclerosis [5], arthritis [6] and even cancer [7].
Such diets provide a broad approach to cancer prevention because they contain many different compounds that can attack the multiple pathways of cancer stem cell survival.