Sentences with phrase «multiple myeloma»

Results from a clinical trial investigating a new T cell receptor (TCR) therapy that uses a person's own immune system to recognize and destroy cancer cells demonstrated a clinical response in 80 percent of multiple myeloma patients with advanced disease after undergoing autologous stem cell transplants (ASCT).

Precious Cat Litter co-founder Kathy Elsey was diagnosed with multiple myeloma in 2009, and she and her husband Bruce have supported the efforts of the MMRF ever since.

Darbepoietin - Alfa after High - Dose Melphalan and Autologous Hemopoietic Progenitor Cell in Multiple Myeloma Patients: A Pilot Study

A new study published online by JAMA Oncology examines the assessment of minimal residual disease in patients newly treated for multiple myeloma as a factor in survival outcomes.

A first - in - human Phase I study of multiple myeloma patients combined expanded cord blood - derived natural killer cells with transplantation of a patient's own stem cells and high - dose chemotherapy with little or none of the side effects seen with current treatments.

MMRF, a 501 (c)(3), is the number one private funder of multiple myeloma research in the United States.

«Updated criteria for diagnosing multiple myeloma published by international research group.»

Johnson & Johnson also has a fast - growing multiple myeloma drug with Darzalex.

The company in - licensed thalidomide in 1992 and received FDA approval to market the drug (as Thalomid) for treating severe cutaneous manifestations of leprosy in 1998 and for treating multiple myeloma in combination with dexamethasone in 2006.

The combination of pomalidomide plus low - dose dexamethasone showed efficacy with high rates of disease control in relapsed or refractory multiple myeloma patients with severe renal impairment, according to the results of a phase II study.

In a new study published in Cancer Letters, American University researchers show how, as body mass index increases, so does the growth and spread of the blood cancer multiple myeloma, which accounts for about 10 percent of all blood cancers in patients.

Cancers of the breast, prostate, colorectal system, liver and kidney as well as multiple myeloma, a cancer of the plasma cells that make antibodies to fight viruses and bacteria, strike earlier, deadlier and more often in some racial and ethnic groups, the National Cancer Institute has shown.

«One - size treatment for blood cancer probably doesn't fit all, researchers say: Most multiple myeloma studies involve people of European descent, but the disease is more likely to affect African - Americans.»

The nanoparticles carry a drug compound that blocks a protein called Myc that is active in many types of cancer, including multiple myeloma.

Supportive care is given to treat problems caused by multiple myeloma and other plasma cell neoplasms.

Eppie died of multiple myeloma at age 83, while Pauline lived to be 94 before succumbing to Alzheimer's disease this year.

«But our findings show that obesity can now be defined as a risk factor for developing multiple myeloma through this condition,» said the study's first author, Su - Hsin Chang, PhD, an assistant professor of surgery in the Division of Public Health Sciences at Washington University.

Role of B - Cell — Activating Factor in Adhesion and Growth of Human Multiple Myeloma Cells in the Bone Marrow Microenvironment

Myeloma is often called multiple myeloma because it occurs at many sites within the bone marrow.

Empliciti will be used in combination with two other drugs to treat patients with multiple myeloma who have received one to three prior courses of medication.

Fat cells cultured from the body mass index of a morbidly obese patient cause multiple myeloma cells to anchor to a much greater extent than normal cells and produce a significantly larger number of blood vessels to sustain the cancer cells.

Because what is true is that a compound in green tea was shown to actually interfere with treatment against multiple myeloma and mantle cell lymphoma.

A randomized phase III trial finding that a new monoclonal antibody, elotuzumab, added to standard therapy, extended the duration of remission for patients with relapsed multiple myeloma by about five months Findings from two phase III studies showing that children with Wilms tumor who have a specific chromosomal abnormality do better with a more intensive, augmented chemotherapy regimen

Little research into multiple myeloma examines varying patient weight to see how cells encourage cancer growth.

Initial treatment for most multiple myeloma patients includes a class of drugs (Revlimid or Pomalyst) broadly known as immune modulators.

Merck multiple myeloma trials on hold after patient deaths.

Also, intriguingly, I hear rumors that there will be some sequencing of less common, largely unexplored cancers like multiple myeloma.

This is called smoldering multiple myeloma.

Sheryl has been fighting multiple myeloma for the past nine years.

Myc inhibitors are thought to be promising treatments for multiple myeloma because they shut down a gene required for cell proliferation.

Kenneth C. Anderson, MD is the Kraft Family Professor of Medicine at Harvard Medical School as well as Director of the Lebow Institute for Myeloma Therapeutics and Jerome Lipper Multiple Myeloma Center at Dana - Farber Cancer Institute.

The results from these studies reflect the real benefits our patients can anticipate from these very important advances in currently available treatment,» said Paul Richardson, clinical program leader and director of clinical research at Dana - Farber's Jerome Lipper Multiple Myeloma Center.

Defining a set of standardised outcome measures for newly diagnosed patients with multiple myeloma using the Delphi consensus method: the IMPORTA project

Bradner and Mitsiades had reported in Cell in 2011 that the inhibitor blocks the Myc cancer gene and thereby slows the growth of multiple myeloma tumors in mice.

They are also testing inhibitors of JAK2, a molecule that influences ADAR1 activity, for their ability to eliminate cancer stem cells in multiple myeloma models.

Diagnostic testing confirmed the diagnosis of multiple myeloma affecting her liver, spleen and bone marrow.

So, in most dogs with multiple myeloma chemotherapy is the treatment of choice.

The mission of the MMRF is to relentlessly pursue innovative means that accelerate the development of next - generation multiple myeloma treatments to extend the lives of patients and lead to a cure.

So far, its trials have shown it can improve outcomes when used alongside other multiple myeloma drugs and that could offer it some insulation if the market gets disrupted by new treatment approaches, such as gene therapy.

Bishop of Bradwell, Rt Rev John Wraw, has died after suffering multiple myeloma, which is a type of bone marrow cancer.

They also found that silencing the ADAR1 gene in the xenograft model reduced multiple myeloma regeneration.

They also determined that blocking the enzyme reduces multiple myeloma regeneration in experimental models derived from patient cancer cells.

«Once a person with cancer is out of the normal weight category, their BMI is contributing to multiple myeloma growth and progression,» said Katie DeCicco - Skinner, associate professor of biology at American University and lead study author.

«Collectively, these Runx2 - mediated effects have the potential to modify the tumor - bone microenvironment and support multiple myeloma cell growth in bone,» Yang and colleagues concluded.

«We know multiple myeloma cells will anchor into bone marrow, and fat cells in the bone marrow will support the growth and spread of the cancer.

«Genetic population heterogeneity of multiple myeloma among patients with African & European ancestry»