The introduced cells contributed to
multiple organ systems in the offspring, the team reports online today in Nature.
Not exact matches
For unknown reasons our immune
system attacks healthy cells, tissues and
organs in a process called autoimmunity, which can result
in diseases such as
multiple sclerosis, type 1 diabetes, lupus or rheumatoid arthritis.
«This research took place at the intersection of microbiology, immunology and genetics, which is illustrative of the complex and synergistic ways
in which
multiple organs and
organ systems operate
in the body.»
The investigators suggest that the premature loss of estrogen caused by the oophorectomy may affect a series of aging mechanisms at the cellular and tissue level across the whole body leading to diseases
in multiple systems and
organs.
«The organism is conservative; it uses the same signaling
systems in multiple organs.»
Tests
in mice and nonhuman primates had shown TGN1412 to be safe, but when it was injected into humans —
in a dose less than 1/500 of what was given to monkeys — it caused a massive release of infection - fighting T cells that overstimulated the patients» immune
systems, resulting
in multiple organ failure.
Dr. Afshar is among the 50 researchers
in Loyola's Alcohol Research Program who are studying the effects of alcohol on
multiple organ systems.
This technical article details
multiple challenges involved
in linking
multiple organs on chips to create
systems that realistically model human physiology.
The Institute also supports research
in certain clinical areas, primarily those that affect
multiple organ systems.
Aging is a physiological phenomenon associated with significant changes
in multiple organs, including hair graying, hearing and memory loss and reduced regeneration ability
in the muscle and hematopoietic
system.
If we decide the threat is real, and that we need to act quickly to reduce its impact, we trigger a cascade of events affecting
multiple systems in our body, including three key endocrine
organs — the hypothalamus and pituitary gland
in our brain, and the adrenal glands that sit atop our kidneys.
In severe cases,
multiple organ systems may also be affected such as the lungs, gastrointestinal tract, kidneys, and the nervous
system.
Given the importance of gonadal hormones
in growth and development, this cultural contrast invites an analysis of the
multiple organ systems that may be adversely affected by neutering.