Sentences with phrase «multiple phases from»

Not exact matches

BIIB098: MRI and relapse results from the phase 3 EVOLVE - MS - 1 study in patients with relapsing and remitting multiple sclerosis were presented at the 70th annual meeting of the American Academy of Neurology (AAN).

What I have learned from many years of working with tech - enabled growth companies; on both sides of mergers and acquisitions; and angel, private equity and venture capital investments, is that accretion of IP value is the key element to supporting overall enterprise value — representing scalability in phases of rapid growth and supporting attractive multiples during the fundraising and exit phases.

During the initial growth phase of your business, there are always multiple responsibilities which take your attention away from certain things you should be focusing on when it comes to pricing your worth.

Product Detail: In Phase II, a company's product is sent through an exhaustive review process with investors basically attempting to poke holes in the company's product thesis from multiple angles.

Fusion Tech has the equipment and experience to handle multiple phases of your plant expansion — from infrastructure to build out to equipment.

A randomized phase III trial finding that a new monoclonal antibody, elotuzumab, added to standard therapy, extended the duration of remission for patients with relapsed multiple myeloma by about five months Findings from two phase III studies showing that children with Wilms tumor who have a specific chromosomal abnormality do better with a more intensive, augmented chemotherapy regimen

«Composite material for water purification: Removal of multiple contaminants from water by supported ionic liquid phases.»

The presence of crystalline grains and multiple iron - bearing phases, including sulfide, in some particles indicates that individual interstellar particles diverge from any one representative model of interstellar dust inferred from astronomical observations and theory.

The study is investigator led and has therefore focused on clinical need, targeting patients with progressive multiple sclerosis in whom most disability is incurred... The study also reports a predominant effect on neurodegenerative rather than inflammatory outcomes, suggesting a novel mechanism of action that might be suitable as combination treatment with immunomodulatory treatments... Further phase 3 studies to measure the effect of simvastatin on sustained disability, particularly in patients with non-relapsing secondary progressive and primary progressive multiple sclerosis, are clearly needed, but this trial represents a promising point from which to develop trials of progressive disease.»

By combining data from multiple studies, Zhang and his colleagues identified six major cycles of warm and cold phases from 1000 to 1911.

-- Poseida Therapeutics released very early data from a Phase 1 study of its CAR - T cell therapy for multiple myeloma.

At the presentations of their research results, the two students showed their findings respectively focused on (i) Accretion and rotational movement of gas around a protostar and the formation of a circumstellar disc and (ii) Identification of bipolar jets (mass ejection) from multiple protostars and classification according to the evolutionary phases.

5a: Jankovic J, Goodman I, Safirstein B, Schenk D, Kinney G, Koller M, Ness DK, Griffith S, Grundman M, Soto J, Ostrowitzki S, Boess F, Martin - Facklam M, Quinn J, Isaacson S, Jennings D, Omidvar O, Ellenbogen A. Results From a Phase 1b multiple ascending - dose study of PRX002, an anti — alpha - synuclein monoclonal antibody, in patients with Parkinson's disease [abstract].

5: Jankovic J, Goodman I, Safirstein B, Schenk D, Kinney GG, Koller M, Ness DK, Griffith SG, Grundman M, Soto J, Ostrowitzki S, Boess FG, Martin - Facklam M, Quinn JF, Isaacson SH, Jennings D, Omidvar O, Ellenbogen A. Results from a Phase 1b multiple ascending - dose study of PRX002, an anti-alpha-synuclein monoclonal antibody, in patients with Parkinson's disease.

Our group has 3 major goals: Develop novel therapeutic approaches based on centrosomal clustering To further develop our first prototype inhibitors of centrosomal clustering preclinically and to establish a robust and specific high throughput small molecule screen Discover key events in myeloma pathogenesis To investigate the pivotal transition from the pre-malignant, asymptomatic to malignant, symptomatic stages of plasma cell dyscrasias in order to understand the pathophysiology and thereby identify novel targets Translate small molecule therapeutics from bench to clinical trials To evaluate novel agents in the preclinical setting and to initiate early phase clinical trials in hematologic malignancies with focus on multiple myeloma

deCODE genetics (Nasdaq: DCGN) today announced positive top - line results from its Phase I multiple dose clinical trial of DG051, which the company is developing for the prevention of heart attack.

During the pilot phase, the Project is analysing Illumina short - read sequence data on 2,512 samples from multiple locations in Africa and Asia, together with laboratory samples for benchmarking and methods development.

MGS was launched in 1996 and the MOC was operated by MSSS for 10 years — from calibration and Mars meteorological imaging during the interplanetary cruise phase, through the spacecraft orbit insertion aerobraking period, the MGS primary mission, and multiple extended missions.

Overall, there is a fine interplay of chemicals from cruciferous vegetables, red wine, spices, teas, and other foods that impact multiple points throughout the phase I detoxification system.

Affleck and Pike are tasked with playing multiple versions of the same characters, and they sell each phase — from deliberately awful rom - com pretensions to claws out bitterness.

The other two phases, as said, are the use of these clues and materials found on the scene to access better and more complex solutions in the dialogue, and then the dialogue itself where you are required to save the target no matter what, with multiple endings which determine whether you'll sacrifice yourself, for example, or throw the both of you from the building.

Great e-book promotion touches all phases of the sales funnel and requires involvement from multiple teams within your organization.

In this time of growing, distributed teams, multiple versions, vendors, and formats, and digital sales, it has never been more important for publishers to actively manage their manuscripts as they move from author to production to post-production phases.

Since then, the hotel gone through multiple phases — from being an officer's quarters during World War II to hosting a Missile Battalion during the Cuban Missile Crisis, the hotel was renovated to the tune of $ 84 in the early 1980s and restored to its original grandeur.

The Preserves offers a variety of wedding packages that include multiple sites for each phase of the wedding, transportation from San Jose, customized catering, booking accommodations for wedding party guests, wedding photographer, and personalized services from an expert events planning team.

Set across five decks of a massive spaceship, robot opponents slash, shoot, launch missiles from their backs, fire screen sweeping lasers and create smaller enemies to attack, while the giant enemy bosses fight with everything they've got across multiple phases.

From the start, the Gallery has been committed to cultivating promising artists in the initial and more advanced phases of their careers exploring contemporary themes and concepts through multiple mediums.The Gallery's original location was a unique industrial indoor / outdoor ground floor space in Williamsburg, Brooklyn - the breeding ground of emerging talent at that time.

It's interesting that you keep pushing geoengineering while at the same time disparaging, rejecting, ignoring and otherwise expressing extreme negativity towards the multiple, readily implementable plans that have been put forward by multiple independent organizations and academic researchers, as well as government agencies, for rapidly phasing out CO2 emissions from fossil fuels using benign technologies that we have at hand now.

Within the paleo - climatological scientific community there is widespread acceptance of millennial cycles during the Holocene because their effects are observed in most climatic proxies, and there is ample agreement over certain periodicities that come out of frequency analysis and are in phase from multiple proxies at different locations.

«From our industries point of view, there are certainly a lot of details that will need to be filled in on multiple different fronts, but in general we're quite supportive of the use of natural gas and the phase out of coal,» CAPP president Tim McMillan said.

Girma Orssengo rightly demonstrates that one can not determine climate sensitivity empirically from observed changes in CO2 concentration and in global mean surface temperature unless one either studies periods that are multiples of ~ 60 years to cancel the transient effects of the warming and cooling phases of the Pacific and related ocean oscillations or studies periods centered on a phase - transition in the ocean oscillations.

During Phase II, testimony will be heard from live witnesses representing stakeholders with interest in multiple sectors of activity, such as Indigenous communities and interest groups.

It allowed me to not only become part of an innovative and dynamic group of people who come from multiple disciplines & backgrounds, but also the opportunity to be actively involved in both (i) the initial planning to the post-construction and operation phase of energy projects across multiple continents and (ii) the strategic formulation, as we move through this current energy transition phase the global energy sector is experiencing, providing me with an amazing intellectual reward and sense of contribution.

Chidambaram said the insurance sector needs to quickly move to the digitization from the voluntary to the mandatory phase as this initiative entails multiple benefits both at the customer end and the insurer end.

But more importantly, I do so in a simple, stress - free, step - by - step system that will guide you quickly, smoothly, and successfully through each phase of your job search — from the initial step of setting your job target to the final steps of negotiating multiple job offers and landing the job you want.

Managed multiple projects simultaneously for various clients from conception through completion phase maintaining timelines and changing requirements for the IVR platform.

Commitment to applying knowledge of multiple operating systems to follow software through all life cycle phases, from initial development through eventual upgrade, to maintain productivity and efficiency.

As a Scientist II I have been requested to assist within many projects within multiple platforms from Assay Architecture (Phase 0 to Phase 1 assay assessment), Point of Care assay and system development teams, Assay and System development for Donor Screening, Immunodiagnostic Assays and Dry Slide Technology platforms, and Site Management for Internal and External Validation Trials for the VITROS 5600/3600 Platforms.

The Chasm Group, LLC and Chasm Institute, LLC (San Bruno, CA) 1997 — 2008 Business Operations Manager • Managed all daily operational tasks for leading multi-million dollar high - tech market strategy consultancy, while providing executive administration to C - level executives and venture capital partners • Developed and managed the firm's annual budget, proposing and implementing expense cuts, producing monthly reports and financial statements, and coordinating with CPA firm for accurate and timely filings • Oversaw all client relationship management efforts while cultivating new business efforts from concept to implementation, providing high - quality service in sales efforts while utilizing new lead tracking system • Negotiated and managed all contracts, stock grants, and financing arrangements, working closely with outside counsel to draft legal documents and resolve LLC - and proprietary - related issues • Led three office space build - outs and two office relocations, managing all aspects of each process under aggressive timeline and budget expectations • Reduced firm telecom expenses by 22 % by streamlining IT objectives, including migration to VOIP phone system, software / hardware purchases, domain renewals, and outsourced technical support • Directed all phases of staff recruitment while creating and implementing all HR policies and programs, including comprehensive employee benefits plans • Supervised multiple administrative staff members, conducted performance appraisals and wage / salary surveys in comparison to incentive program guidelines, and maintained HR files in accordance with legal mandates • Produced all out - going client invoices in an accurate and timely fashion to increase, cash flow and reduce aging receivables, providing consistent attention to overhead costs and vendor arrangements • Administered all company insurance policies, including E&O, general liability, bonds, partner life and disability, conducting annual benefits reviews and employee / company insurance audits • Obtained necessary certificates for consulting contracts while processing federal, state, and local business reporting requirements to maintain licenses and incorporation status • Directed all marketing efforts and oversaw logistical aspects of national educational workshop series, utilizing sponsorship arrangements to offset production costs • Transformed «brochure» website into a dynamic tool to better illustrate company opportunities through relevant case studies, as well as maintaining all other promotional media, including press kits and video Association of California School Administrators (Burlingame, CA) 1993 — 1997 Issues and Planning Committee Coordinator • Executed all phases of event planning and implementation for a membership - driven organization including 23 state committees, 5 task forces, 6 strategic planning conferences, and a conference of 1,500 attendees • Focused on facility evaluations, bid requests, site visits, contract negotiations, and all pre - and post-conference planning processes • Produced statistical and financial reports, including budget projections and cost monitoring for developmental training efforts • Oversaw all participant - level responsibilities, including inquiries, eligibility, registration, correspondence, and billing statements • Managed all legal professional standards calls for Northern California regions, including the processing of attorney authorizations, the preparation of legal assistance letters, and liens on cause of action • Served as second point of contact for computer inquiries and troubleshooting efforts as well as provided back - up executive administrative support for Executive Director, Committee Chairs, and the State Superintendent of Public Instruction • Held responsibility for software installation and hardware configuration while performing weekly AS / 400 backup and report generation

SUMMARY: 30 years Clinical Research and home - based monitoring experience 12 years Oncology monitoring experience 12 years Pediatric Nurse experience Largest workload: 5 - 6 protocols with 10 - 15 sites in Oncology - Non-Small Cell Lung - Phase III, Neurology - Multiple Sclerosis - Phase III while at EMD Serono 10 years experience with Inform EDC and 6 months experience with IMedidata Located 20 minutes from Baltimore Washington Inter...

We have just launched Phase 1 of the review by posting a consultation paper on the Ontario Regulatory Registry to get input from consumers and industry professionals on various areas of concern including important measures to address the practice of multiple representation or «double - ending».