HuH - 7 (human HCC), HepG2 (human hepatocellular blastoma), 293T (human
embryonic kidney
fibroblast), HeLa (human cervical cancer cells), NIH 3T3 (
murine fibroblast), and HCT116 (human colon cancer) and its derived cell line HCT116 p21 − / − (kindly provided by Dr. B. Vogelstein, Howard Hughes Medical Institute, Chevy Chase and the Sydney Kimmel Comprehensive Cancer Center of the Johns Hopkins University School of Medicine, Baltimore, MD; ref.