ADCC / ADCP - enabling isotypes of a-TIGIT surrogate Ab show potent monotherapy efficacy in
murine tumor models that correlates to increased T cell activation and reduced Treg infiltration of tumors.
Not exact matches
Moreover, experiments on an ovarian cancer
murine model that investigated the effects of orally administered ONA resulted in longer lifespans and inhibited ovarian cancer
tumor development.
«Preclinical results support entinostat's role in targeting the
tumor microenvironment: Entinostat inhibits function of myeloid derived suppressor cells resulting in enhanced antitumor effect in
murine models of lung and renal cell carcinoma.»
Direct
Tumor Vaccination Shown to Induce Anti-
Tumor Immunity and Increase Survival in a
Murine Model of Pancreatic Cancer MedicalNewsToday.com - March 27, 2017
Her background in molecular biology, cell biology, and
tumor biology, as well as publications of her research, has prepared Dr. Vines to study the regulation of CCR7 - mediated
tumor responses in selected
murine models.
(G) Immunostaining of p - ERK in
tumor samples of xenografted
murine models bearing KMT2D V5486 mutants treated with CHID and / or DECI.