Sentences with phrase «muscle cell dysfunction»

In addition to LOX - 1 mediated vascular inflammation, oxLDL / LOX -1 internalization triggers endothelial / vascular smooth muscle cell dysfunction, apoptosis, cellular senescence, or osteoblastic differentiation.

Not exact matches

The main cause of this beta cell dysfunction is the accumulation of fat inside your muscle and liver (2 — 7).

Saturated fat causes more of those toxic breakdown products and mitochondrial dysfunction, and increases oxidative stress, free radicals, and inflammation, establishing a vicious cycle of events in which saturated fat - induced free radicals cause dysfunction in the little power plants within our muscle cells, which causes an increase in free radical production and the impairment of insulin signaling.

For example, Dr. Greger discusses a» vicious cycle of events in which saturated fat induced free radicals causes dysfunction in the little powerplants within our muscle cells, which causes an increase in free production and impairment of insulin signaling.»

Their metabolites accumulate in muscle and fat cells, activate proinflammatory signalling cascades, cause mitochondrial dysfunction, and interfere with insulin - stimulated glucose transport.

Hirabara SM, Curi R, Maechler P. Saturated fatty acid - induced insulin resistance is associated with mitochondrial dysfunction in skeletal muscle cells.

Endothelial cell activation, vascular smooth muscle dysfunction, oxidative stress, and inflammation, mechanisms which underlie heart disease, diabetes, and hypertension, are all variables which can precipitate or perpetuate immune imbalances in autoimmune disease.

Glutathione is a potent antioxidant, so its deficiency will further contribute to dysfunction of the muscle cell's mitochondria, therefore greatly impairing its energy supply.

Vascular endothelial dysfunction promotes vasoconstriction and favors platelet aggregation, white blood cell adhesion, and smooth muscle cell proliferation.