Because the TSG12 specifically targets
the muscle cells involved in asthma, it may also have fewer side effects than beta - 2 agonists.
Not exact matches
Everyday influences — the weights Dad lifts to make himself
muscle - bound, the diet regimen Mom follows to lose pounds — don't produce stronger or slimmer progeny, because those changes don't affect the germ
cells involved in making children.
To see which are
involved in heart -
cell division, Giacca's team tested 875 human microRNAs in cultured rodent heart
muscle.
Researchers at the University of Louisville have discovered a mechanism
involved in skeletal
muscle repair that may enable clinicians to boost the effectiveness of adult stem
cell therapies for diseases such as muscular dystrophy.
Svendsen is more optimistic about his team's work
involving human tests of a novel stem
cell approach to treat ALS, a degenerative motor neuron disease in which
cells that transmit messages from the brain and spinal cord to the
muscles wither or die.
Previous research by Lee's lab had shown that p75 is
involved in a signaling pathway that regulates the development of sensory neurons —
cells which transmit our sensation of pain, touch and
muscle tension — in the dorsal root ganglia.
Scientists have discovered a way in which proteins in our
cells help to control genes in our DNA, which are
involved in forming
muscle.
We found 20 genes that distinguished motor neurons that innervate digit
muscles from the others, and there's a strange gene code
involved in the
cells» development.
The research team analyzed heart
muscle cells to identify enzymes
involved in metabolizing fuel that may ultimately become targets for therapies.
Atala's method
involved painting several coats of Kaitlyne's
muscle cells on the outer surface of a bladder - shaped mold made of collagen.
As development proceeds, neural crest
cells break away, migrating from head to toe to form tissues
involved in pigmentation,
muscles, teeth, bone, cartilage, and adrenal glands, which produce stress hormones as well as testosterone.
In the case of muscular dystrophy, the chronic cycles of
muscle regeneration and degeneration that
involve satellite -
cell activation exhaust the
muscle stem -
cell pool to the point of no return.
Bones support body structures, protect internal organs, and (in conjunction with
muscles) facilitate movement; are also
involved with
cell formation, calcium metabolism, and mineral storage.
«People used to think that this region of the medulla was only
involved in the paralysis of skeletal
muscles during REM sleep,» said lead author Yang Dan, a UC Berkeley professor of molecular and
cell biology and a Howard Hughes Medical Institute Investigator.
They found that BET proteins regulate the growth of heart
muscle cells and activate a broad set of genes
involved in heart failure.
Connective tissue
cells, but not
muscle cells, are
involved in establishing the proximo - distal outcome of limb regeneration in the axolotl.
MyoD is normally only expressed in skeletal
muscle, and it was later found to be a transcription factor
involved in the differentiation of
muscle cells and also a very early marker of
muscle cell fate commitment.
Providing rigidity to the
cell, actin filaments are
involved in a host of processes including
muscle contraction,
cell mobility and
cell division.
Spinal muscular atrophy
involves wasting of the skeletal
muscles and is caused by gradual degeneration of nerve
cells in the spinal cord.
These factors work together to activate genes
involved in fashioning heart
muscle cells, while suppressing genes characteristic of other
cell types.
1) The first mechanism
involves the synthesis of protein that is taking place within the
muscle cell, including all segments of its structure like the connective tissues,
cell walls and contractile elements.
2) The other mechanism is much more simpler, yet much more obscure and
involves swelling of the
cells that doesn't affect the function of the
muscles.
While
muscle hypertrophy focuses on building the
muscle's fibres and
cells, strength is neurologically focused and
involves conditioning the nervous system to withstand a greater force of stress.
Researchers have demonstrated that celery phthalides can act as smooth
muscle relaxants, most likely through their impact on the flow of calcium and potassium inside
cells and related nervous system activity
involved with
muscle relaxation.
1) Phytonutrients: * Occur naturally in fruits and vegetables * Promote the function of the immune system * Help fight off viruses as well as reduce inflammation * Associated with the treatment and / or prevention of cancer and cardiovascular disease 2) Enzymes: * Responsible for metabolic processes that occur within a
cell and are necessary for sustaining life * Assist and play a large role in digestion, energy production, blood coagulation and contraction of
muscles 3) Amino Acids: * The basic building blocks of protein * Absorption of amino acids is essential for your metabolism 4) Essential Fatty Acids: * Reduce the risk of heart disease and some forms of cancer * Improve mood * Decrease inflammation 5) Vitamins: * Essential for the normal growth and development of all human beings * Healthy maintenance of
cell tissues and organs * Help process proteins, carbohydrates and fats required for utilization 6 & 7) Macro and Trace Minerals: *
Involved in electrolyte balance of body fluids * Essential for normal cellular activity * Provide hardness to bones and teeth
It's well known that one chemical pathway by which
muscle cells grow
involves growth hormone and one of its subset, IGF - 1.
EDR activity
involves the release of endothelial nitric oxide (NO) release and subsequent increase in cyclic guanosine monophosphate (GMP) levels in the vascular smooth
muscle cells ultimately increasing vasodilation and blood flow.
Future use of IGF - 1 will no doubt
involve gene therapy, which directly targets genes that produce IGF - 1 in
muscle, usually by attaching specific gene activators to an inactive virus or vector that then enters into
muscle cells.
Children with asthma have lower vitamin A levels than children without asthma, and the degree of vitamin A deficiency they exhibit is directly proportional to the severity of their asthma.37, 38 In
cell experiments, vitamin A eliminates the response of bronchial smooth
muscle cells to growth factors that characterizes the asthmatic reaction39 and suppresses the activity of mast
cells, which are
involved in asthmatic or other reactions mediated by histamine or other inflammatory chemical messengers called leukotrienes.40 Consistent with studies in isolated
cells, vitamin A deficiency causes asthmatic bronchial hyper - reactivity in live rats.41
This requirement may increase along with the extension of activities that you are
involved in, since you need enough to provide for the
muscle repair and recovery as well as need protein for basic functions like enzyme production, hormonal balance,
cell production, etc..
At the beginning of such anaerobic exercise (
involving metabolic processes without oxygen), the
muscle cells must therefore resort to energy sources which are immediately available.
Your body adapts by activating more fibers in the
muscles involved in a certain movement (meaning your nervous system adapted by firing signals to more
muscle cells).
Very much in the same way that an overtaxed
muscle will twitch briefly before giving way, nerve
cells of the cerebral cortex
involved in running the task appear to be forced, by lack of fuel, to simply tap out for the moment, leaving you no choice but to take a break.
Leucine facilitates the insulin - stimulated glucose uptake and insulin signaling in skeletal
muscle cells:
involving mTORC1 and mTORC2.
The recent recognition that de novo lipogenesis might have relevance for lipid homeostasis in skeletal
muscle stems from the realization that Sterol regulatory element binding protein - 1c (SREBP - 1c), a member of the family of transcription factors that regulate the expression of genes
involved in lipid storage in liver and adipose tissue, is also present in skeletal
muscle at a level close to that observed in the liver, 41,42... [M] ost fascinating are the very recent demonstrations that glucose alone (in the absence of insulin) can stimulate de novo lipogenesis in skeletal
muscle cells....
You start to breathe more oxygen and trough the blood it comes to
muscles and all
cells involved in exercises.
Calcium is a mineral that supports
muscle function, transmits nerve impulses to help
cells communicate with each other, and is
involved in the release of certain hormones.
This second set of experiments in cultured
muscle cells showed that HMB attenuated a specific pathway
involving caspase 3 and 8, PKR (RNA dependent protein kinase), and reactive oxygen species (ROS) known to activate the ubiquitin - protease pathway.
Another group of
cells is
involved in repairing the damaged
muscle tissue.
The practice of yoga poses which
involves stretching of
muscles, moving of organs around, etc. increases the evacuation of lymph (a viscous fluid containing white blood
cells).
Then second component of
muscle memory
involves your
cells.
Creatine can increase
muscle fiber size by increasing water content in your
muscle cells, which triggers genes
involved in increasing size.
ACT - activated clotting time (bleeding disorders) ACTH - adrenocorticotropic hormone (adrenal gland function) Ag - antigen test for proteins specific to a disease causing organism or virus Alb - albumin (liver, kidney and intestinal disorders) Alk - Phos, ALP alkaline phosphatase (liver and adrenal disorders) Allergy Testing intradermal or blood antibody test for allergen hypersensitivity ALT - alanine aminotransferase (liver disorder) Amyl - amylase enzyme — non specific (pancreatitis) ANA - antinuclear antibody (systemic lupus erythematosus) Anaplasmosis Anaplasma spp. (tick - borne rickettsial disease) APTT - activated partial thromboplastin time (blood clotting ability) AST - aspartate aminotransferase (
muscle and liver disorders) Band band
cell — type of white blood
cell Baso basophil — type of white blood
cell Bile Acids digestive acids produced in the liver and stored in the gall bladder (liver function) Bili bilirubin (bile pigment responsible for jaundice from liver disease or RBC destruction) BP - blood pressure measurement BUN - blood urea nitrogen (kidney and liver function) Bx biopsy C & S aerobic / anaerobic bacterial culture and antibiotic sensitivity test (infection, drug selection) Ca +2 calcium ion — unbound calcium (parathyroid gland function) CBC - complete blood count (all circulating
cells) Chol cholesterol (liver, thyroid disorders) CK, CPK creatine [phospho] kinase (
muscle disease, heart disease) Cl - chloride ion — unbound chloride (hydration, blood pH) CO2 - carbon dioxide (blood pH) Contrast Radiograph x-ray image using injected radiopaque contrast media Cortisol hormone produced by the adrenal glands (adrenal gland function) Coomb's anti- red blood
cell antibody test (immune - mediated hemolytic anemia) Crea creatinine (kidney function) CRT - capillary refill time (blood pressure, tissue perfusion) DTM - dermatophyte test medium (ringworm — dermatophytosis) EEG - electroencephalogram (brain function, epilepsy) Ehrlichia Ehrlichia spp. (tick - borne rickettsial disease) EKG, ECG - electrok [c] ardiogram (electrical heart activity, heart arryhthmia) Eos eosinophil — type of white blood
cell Fecal, flotation, direct intestinal parasite exam FeLV Feline Leukemia Virus test FIA Feline Infectious Anemia: aka Feline Hemotrophic Mycoplasma, Haemobartonella felis test FIV Feline Immunodeficiency Virus test Fluorescein Stain fluorescein stain uptake of cornea (corneal ulceration) fT4, fT4ed, freeT4ed thyroxine hormone unbound by protein measured by equilibrium dialysis (thyroid function) GGT gamma - glutamyltranferase (liver disorders) Glob globulin (liver, immune system) Glu blood or urine glucose (diabetes mellitus) Gran granulocytes — subgroup of white blood
cells Hb, Hgb hemoglobin — iron rich protein bound to red blood
cells that carries oxygen (anemia, red
cell mass) HCO3 - bicarbonate ion (blood pH) HCT, PCV, MHCT hematocrit, packed -
cell volume, microhematocrit (hemoconcentration, dehydration, anemia) K + potassium ion — unbound potassium (kidney disorders, adrenal gland disorders) Lipa lipase enzyme — non specific (pancreatitis) LYME Borrelia spp. (tick - borne rickettsial disease) Lymph lymphocyte — type of white blood
cell MCHC mean corpuscular hemoglobin concentration (anemia, iron deficiency) MCV mean corpuscular volume — average red
cell size (anemia, iron deficiency) Mg +2 magnesium ion — unbound magnesium (diabetes, parathyroid function, malnutrition) MHCT, HCT, PCV microhematocrit, hematocrit, packed -
cell volume (hemoconcentration, dehydration, anemia) MIC minimum inhibitory concentration — part of the C&S that determines antimicrobial selection Mono monocyte — type of white blood
cell MRI magnetic resonance imaging (advanced tissue imaging) Na + sodium ion — unbound sodium (dehydration, adrenal gland disease) nRBC nucleated red blood
cell — immature red blood
cell (bone marrow damage, lead toxicity) PCV, HCT, MHCT packed -
cell volume, hematocrit, microhematocrit (hemoconcentration, dehydration, anemia) PE physical examination pH urine pH (urinary tract infection, urolithiasis) Phos phosphorus (kidney disorders, ketoacidosis, parathyroid function) PLI pancreatic lipase immunoreactivity (pancreatitis) PLT platelet —
cells involved in clotting (bleeding disorders) PT prothrombin time (bleeding disorders) PTH parathyroid hormone, parathormone (parathyroid function) Radiograph x-ray image RBC red blood
cell count (anemia) REL Rocky Mountain Spotted Fever / Ehrlichia / Lyme combination test Retic reticulocyte — immature red blood
cell (regenerative vs. non-regenerative anemia) RMSF Rocky Mountain Spotted Fever SAP serum alkaline phosphatase (liver disorders) Schirmer Tear Test tear production test (keratoconjunctivitis sicca — dry eye,) Seg segmented neutrophil — type of white blood
cell USG Urine specific gravity (urine concentration, kidney function) spec cPL specific canine pancreatic lipase (pancreatitis)-- replaces the PLI test spec fPL specific feline pancreatic lipase (pancreatitis)-- replaces the PLI test T4 thyroxine hormone — total (thyroid gland function) TLI trypsin - like immunoreactivity (exocrine pancreatic insufficiency) TP total protein (hydration, liver disorders) TPR temperature / pulse / respirations (physical exam vital signs) Trig triglycerides (fat metabolism, liver disorders) TSH thyroid stimulating hormone (thyroid gland function) UA urinalysis (kidney function, urinary tract infection, diabetes) Urine Cortisol - Crea Ratio urine cortisol - creatine ratio (screening test for adrenal gland disease) Urine Protein - Crea Ratio urine protein - creatinine ratio (kidney disorders) VWF VonWillebrands factor (bleeding disorder) WBC white blood
cell count (infection, inflammation, bone marrow suppression)