Sentences with phrase «muscle stem cells as»

Using mouse skeletal muscle stem cells as a model, we show that accumulating transcripts specifying the myogenic program are not translated in quiescent satellite cells, but are repressed by the action of microRNAs and RNA binding proteins.

Experimental approaches such as gene therapy are also being investigated, but Dr. Rudnicki's research suggests that these approaches will have to be modified so that they target muscle stem cells as well as muscle fibres.

Not exact matches

Instead, LaFlamme's research team in Toronto is taking a different approach through injecting a billion heart - muscle cells (otherwise known as cardiomyocytes) that have been developed from stem cells.

Specialized stem cells known as satellite cells reside in skeletal muscle in an inactive state.

The investigators found that when LIF - treated muscle stem cells were transplanted to skeletal muscle, they formed two to three times more muscle fibers as control cells did.

Researchers at the University of Louisville have discovered a mechanism involved in skeletal muscle repair that may enable clinicians to boost the effectiveness of adult stem cell therapies for diseases such as muscular dystrophy.

Current research is looking at why inhibiting certain molecules, such as mouse protein Stat3, promote muscle regeneration in mice and how to engineer orthopedic implants from stem cells to replace damaged cartilage and bone, but the results of that effort aren't expected to be necessarily aimed at the old.

First, the cells are grown in defined supplements without animal products such as bovine serum, enhancing the clinical safety for the muscle stem cells.

Around 2000, then - postdoc Wagers and other researchers in Irving Weissman's and Thomas Rando's labs at Stanford revived the method, known as parabiosis, to study the fate of blood stem cells and muscle cells.

Various reports in recent years have claimed that stem cells from one tissue — for example, blood — can mature into other tissues such as muscle or brain.

Adult stem cells: They have less flexibility and «stemness» to change into different cell types, but they can still produce new cells, specialized to become part of a particular organ or tissue, such as muscle cells or neural cells.

The researchers traced stem cells as they matured into motor neurons, which are the type of nerve cells that control muscle movement.

Normally, adult stem cells can only morph into the type of tissue in which they reside, such as blood, brain or muscle.

First, when muscle is damaged by injury or degenerative disease such as muscular dystrophy, muscle stem cells — or satellite cells — need to differentiate into mature muscle cells to repair injured muscles.

Labs use induced pluripotent stem cells, also known as master cells, which using biochemical cues can be «programmed» to become any type of cell, whether for the heart muscle or otherwise.

Although unequal division occurs among stem cells — allowing one daughter cell to remain a stem cell while the other matures into another cell type, such as a skin or muscle cell — the goal of a normal symmetric cell division is to generate identical daughter cells and increase cell number.

Johns Hopkins University biologists have found that a protein that plays a key role in the lives of stem cells can bolster the growth of damaged muscle tissue, a step that could potentially contribute to treatments for muscle degeneration caused by old age and diseases such as muscular dystrophy.

The presence of the protein β1 - integrin was shown to help promote the transformation of those undifferentiated stem cells into muscle after the tissue has degraded, and improve regenerated muscle fiber growth as much as 50 percent.

As stem cells continue their gradual transition from the lab to the clinic, a research group at the University of Wisconsin — Madison has discovered a new way to make large concentrations of skeletal muscle cells and muscle progenitors from human stem cells.

When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell (Fig 1).

As part of this effort, Xu and her team discovered that growing stem cells under «simulated microgravity» for a few days stimulates the production of cardiac muscle cells, several times more effectively than regular conditions.

Researchers report a surprisingly easy method to change a specialized cell, such as muscle or bone, into becoming a universal stem cell.

While it is generally accepted that MSC are mostly quiescent during postnatal life, MSCs in different niches can presumably differentiate into the specific cells of closely related niches during physiological turnover, injury or disease, as shown for other stem cell types (e.g., muscle satellite cells).

For quality control, researchers want to figure out how to ensure that the stem - cell - derived cardiac muscle or neural progenitor or pancreas cells (or whatever) are as pure as possible.

In the present seminar, I will summarize our findings concerning the role of Srf in myofibers to control muscle mass and I will present recent data identifying Srf as a master regulator of muscle stem cell fusion and demonstrating the implication of F - actin architecture in this process.

Satellite cells were discovered decades ago (Mauro, 1961) and are commonly simply (and perhaps confusingly) referred to as muscle stem cells.

Skeletal muscle stem cells propagated as myospheres display electrophysiological properties modulated by culture conditions.

The in vitro expansion of muscle stem cells (MuSCs), also known as satellite cells, may provide a potent means to treat a wide range of muscle - related diseases such as sarcopenia and muscular dystrophy.

Stem cells from the bone marrow can develop into cardiac muscle, as well as liver, brain, nerve, fat and skin tissue.

4 - 1BBL was largely thought to be on APC that have been activated for several days, such as dendritic cells, B cells, and macrophages although again it is clear that 4 - 1BBL is now more ubiquitous as it has been visualized to be induced on diverse cell types such as mast cells, osteoclasts, smooth muscle, and stem cells.

Stem cells are cells found primarily in embryos, and they have not yet taken on the characteristics of any particular type of cell, such as bone, muscle tissue or brain matter.

In a study using human muscle tissue, scientists in Children's Stem Cell Research Center - led by Johnny Huard, PhD, and Bruno Péault, PhD - isolated and characterized stem cells taken from blood vessels (known as myoendothelial cells) that are easily isolated using cell - sorting techniques, proliferate rapidly and can be differentiated in the laboratory into muscle, bone and cartilage ceStem Cell Research Center - led by Johnny Huard, PhD, and Bruno Péault, PhD - isolated and characterized stem cells taken from blood vessels (known as myoendothelial cells) that are easily isolated using cell - sorting techniques, proliferate rapidly and can be differentiated in the laboratory into muscle, bone and cartilage ceCell Research Center - led by Johnny Huard, PhD, and Bruno Péault, PhD - isolated and characterized stem cells taken from blood vessels (known as myoendothelial cells) that are easily isolated using cell - sorting techniques, proliferate rapidly and can be differentiated in the laboratory into muscle, bone and cartilage cestem cells taken from blood vessels (known as myoendothelial cells) that are easily isolated using cell - sorting techniques, proliferate rapidly and can be differentiated in the laboratory into muscle, bone and cartilage cecell - sorting techniques, proliferate rapidly and can be differentiated in the laboratory into muscle, bone and cartilage cells.

Secondly, stem cells are unspecialized, which means they don't have a unique function, such as pumping blood to the heart or supporting muscles in the legs.

Adult stem cells serve as a reservoir of cells for repair of damaged tissue throughout the life of an individual, but the maintenance and regeneration of tissues, such as skin, liver, blood and muscle, dramatically decrease with age.

After a very extended childhood spent dividing in a culture dish, even stem cells tend to grow up and assume adult roles as workaday nerve, muscle, or blood cells, never to return to their youthful state.

As our bones, muscle, or cartilage wear out, our body uses stem cells to replace them.

Brown fat cells come from the same stem cells as muscle.

Prolotherapy fits into the same category as stem cell therapy — something to consider when you need to «take out the big guns» on a joint or muscle injury that just won't go away.

Stem cells can divide and turn into tissues such as skin, fat, muscle, bone, cartilage and nerve, to name a few.

In terms of fat - derived stem cells, progress has been made in several areas of canine health, including muscle inflammation and a disease known as immune - mediated anemia, which is when the immune system destroys red blood cells, leaving your dog weak and listless.

Stem cell therapy offers the possibility of using these stem cells to grow into replacements for injured or diseased tissues such as bone, cartilage, muscle, nerves, and soStem cell therapy offers the possibility of using these stem cells to grow into replacements for injured or diseased tissues such as bone, cartilage, muscle, nerves, and sostem cells to grow into replacements for injured or diseased tissues such as bone, cartilage, muscle, nerves, and so on.

Students will experience in house diagnostics, primary care, acupuncture, chiropractic, holistic nutrition, muscle testing, surgery, radiology, therapeutic laser treatments, ozone therapy, stem cell therapy, platelet rich plasma regenerative therapy, and physical rehabilitation therapy as well as surgical procedures, and digital radiology.

While one stem cell sample from a beef cow can eventually produce up to 20,000 tons of meat, thus far scientists must feed the cells to help them grow, as well as treating the final meat muscle with «accepted food technology methods» to make it taste like what we expect.

«Statins make regular users become older faster, leaving them open to long - term mental and physical decline, according to disturbing new research... Scientists have found the heart disease drug badly affects our stem cells, the internal medical system which repairs damage to our bodies and protects us from muscle and joint pain as well as memory loss.»