«These progenitor cells resemble adult
muscle stem cells called «satellite cells» that can theoretically grow an entire muscle starting from a single cell.»
Not exact matches
One of the molecular mysteries hindering development of regenerative therapy for
muscles is uncovering the precise genetic and molecular processes that cause skeletal
muscle stem cells (
called myoblasts) to fuse and form the striated
muscle fibers that allow movement.
Two weeks after the experimental myocardial infarctions, the Seattle researchers injected 1 billion heart
muscle cells derived from human embryonic
stem cells,
called human embryonic
stem cell - derived cardiomyocytes, into the infarcted
muscle.
In a related paper published online today in Nature Biotechnology, Konrad Hochedlinger of the Harvard
Stem Cell Institute in Cambridge and his colleagues compared the gene expression patterns in mouse iPS
cells derived from white blood
cells,
muscle precursor
cells, immune system
cells called B
cells, and fibroblasts taken from tail tips.
The pluripotent
stem cells are then grown while being flooded with a molecule
called Pax7 — which signals the
cells to start becoming
muscle.
In a new study, doctoral student Cajsa Davegårdh has studied so -
called DNA methylation in
muscle stem cells in both obese and non-obese individuals.
The experiment shows that β1 - integrin — one of 28 types of integrin — maintains a link between the
stem cell and its environment, and interacts biochemically with a growth factor
called fibroblast growth factor [FGF] to promote
stem cell growth and restoration after
muscle tissue injury.
Within a hair follicle, there are
stem cells that reside in an area
called the hair follicle «bulge,» which is a small compartment located where the outer root sheath meets the arrector pili
muscle (see Hair Follicle figure).
A team led by Dr. Alexey Terskikh at Sanford - Burnham Medical Research Institute (Sanford - Burnham) recently found that expression of a gene
called SOX2 maintains the potential for neural crest
stem cells to become neurons in the peripheral nervous system, where they interface with
muscles and other organs.