Sentences with phrase «muscle weakness affecting»

Clinically affected dogs are often young (3 - 18 months of age) and present with poor weight gain, progressive peripheral neuropathy including ataxia, leg crossing, tremors and paresis which worsens with exercise.Behavioral changes, blindness, dementia, anorexia, cachexia, urinary incontinence and muscle weakness affecting all four limbs are usually present in terminal stages of the disease with death occurring 2 - 6 months after onset of clinical signs, necessitating euthanasia.

Not exact matches

Audentes Therapeutics is focused on rare genetic diseases that affect muscles, including the heart, or reduce their victims to muscular weakness.
Motor neurons in the spinal cord are affected, resulting in muscle weakness and in many cases breathing problems.
The study, led by Dr Yalda Jamshidi from St George's, University of London and Dr Chiara Manzini from George Washington University, examined the DNA of five individuals who were affected by early onset of a group of conditions including muscle weakness and an inability to stand or walk.
Stroke patients generally show muscle weakness of limbs and trunk on the affected side.
Walking performance is often affected by muscle weakness, spasticity, contracture, pain, sensory and visual impairments, and postural instability.
This supportive approach has improved the natural history of SMA by extending life expectancy, but muscle weakness and atrophy are not affected.
SMA is a genetic neuromuscular disorder that causes muscle weakness and one in every 10,000 children born is affected by it.
For example, knowing that the SMA mutation causes debilitating muscle weakness, researchers might be able to target treatments to address that problem even if they don't have a therapy that would affect the motor neurons themselves.
Muscle cell damage can progress to atrophy and weakness, and because the heart muscle cells are affected to, can even lead to heart faMuscle cell damage can progress to atrophy and weakness, and because the heart muscle cells are affected to, can even lead to heart famuscle cells are affected to, can even lead to heart failure.
Any unexplained tingling that affects one side of the body or is accompanied by muscle weakness warrants immediate medical attention.
Men and women have huge differences in their body compositions, joint alignments and connective tissues, all of which affect their muscle strengths, weaknesses, and susceptibility to injury, says exercise physiologist and trainer Marta Montenegro, MS, CSCS.
They also notice weakness in their muscles which affects their day to day activities.
Distal weaknessweakness of muscles further out on the limbs — is estimated to affect 30 percent of people with hypothyroidism.
Statin, however, would also cause some dangerous side effect — especially muscle pain, tiredness or muscle weakness, as statins affect not only liver's production of cholesterol, but also several enzymes in muscle cells that are responsible for muscle growth.
VS may also affect people causing a mild flu - like illness with symptoms of fever, weakness and muscle aches.
Many animals with chronic arthritis have loss of muscle mass and increased weakness due to the decreased use of the affected limb or limbs.
Dilated Cardiomyopathy (DCM) is a condition characterized by weakness of the heart muscle (poor contractility) that eventually leads to enlargement (dilation) of the heart chambers and complications of congestive heart failure, irregular heart rhythms (arrhythmias), and / or sudden death in affected individuals.
Generalized myopathy: a condition affecting all the muscles of the body which produces weakness.
Both arthritis and obesity limit mobility, negatively affects cartilage, which in turn results in muscle atrophy and weakness.
If there is excessive loss of potassium this can lead to generalized muscle weakness, paralytic ileus, and even cardiac arrhythmias which can adversely affect the delivery of oxygen and nutrients to the cells.
Low blood potassium affects heart rhythm and causes muscle weakness.
Affected dogs will self - limit their activity due to muscle weakness and pneumonia, if it is present.
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