Sentences with phrase «muscular diseases caused»

Muscular dystrophy is a term used to describe many different muscular diseases caused by genetic defects.

Not exact matches

• Exonics Therapeutics, Inc, a Boston - based biotechnology company focused on developing SingleCut CRISPR technology to repair mutations causing Duchenne muscular dystrophy and other neuromuscular diseases, raised $ 40 million in Series A funding.

According to studies, approximately one out of every 40 individuals in the United States is a carrier of the gene responsible for spinal muscular atrophy (SMA), a neurodegenerative disease that causes muscles to weaken over time.

Spinal muscular atrophy (SMA) is a devastating hereditary disease that is a leading cause of infant and early childhood mortality.

According to recent studies, approximately one out of every 40 individuals in the United States is a carrier of the gene responsible for spinal muscular atrophy (SMA), a neurodegenerative disease that causes muscles to weaken over time.

Knowing the sex of a fetus is important when the mother is a carrier of an X-chromosome gene that can cause a disease such as muscular dystrophy.

They had been working with a worm model of Duchenne muscular dystrophy, a severe form of the disease that strikes young boys and is caused by mutations in the gene that encodes the dystrophin protein.

Muscular dystrophy, a disease caused by a genetic mutation on the X chromosome, primarily affects boys and comes in several varieties.

In the last four years scientists have cloned and sequenced many genes carrying defects that cause disease, including those responsible for Fragile X linked mental retardation, different forms of muscular dystrophy, and most recently Huntington's disease.

This balance can be disrupted in diseases such as Duchenne muscular dystrophy, which is caused by the lack of a muscle - specific protein, dystrophin.

Spinal muscular atrophy is a debilitating disease that causes weakness and wasting of the muscles.

LONDON — Wellcome Trust, the United Kingdom's largest biomedical research charity, today announced more than # 4 million in support for a pioneering, and potentially controversial, IVF treatment that could prevent some forms of muscular dystrophy and other diseases caused by defective mitochondria, the energy - generating organelle in cells.

Johns Hopkins University biologists have found that a protein that plays a key role in the lives of stem cells can bolster the growth of damaged muscle tissue, a step that could potentially contribute to treatments for muscle degeneration caused by old age and diseases such as muscular dystrophy.

Myopathies are frequent diseases and can be caused by inherited genetic defects (e.g., muscular dystrophies), or by endocrine inflammatory (e.g., polymyositis), and metabolic disorder.

Spinal Muscular Atrophy (SMA) is a motor neuron disease and the leading genetic cause of death among infants and toddlers.

Bar Harbor, Maine — October 21, 2004 — The Jackson Laboratory is pleased to announce that it has received support from the Spinal Muscular Atrophy Foundation to make available the first group of mouse models for spinal muscular atrophy (SMA), a neuromuscular disease and the leading genetic cause of death among infants and tMuscular Atrophy Foundation to make available the first group of mouse models for spinal muscular atrophy (SMA), a neuromuscular disease and the leading genetic cause of death among infants and tmuscular atrophy (SMA), a neuromuscular disease and the leading genetic cause of death among infants and toddlers.

Spinobulbar muscular atrophy, another neurodegenerative disease caused by increased CAG size

It is characterized by the wasting of skeletal muscles and caused by progressive degeneration of nerve cells in the spinal cord; the disease leads to increasing muscular weakness, atrophy and premature death due to respiratory problems.

This year's ASENT meeting featured a symposium on spinal muscular atrophy (SMA), an inherited motor neuron disease that is the second most common autosomal recessive disorder of children and the most common genetic cause of death in infancy, as a case study in neurology orphan drug development.

Spinal muscular atrophy is a genetic disease that causes the degeneration of spinal cord motor neurons and leads to progressive muscle weakness, atrophy and inability to walk or sit, and breathing difficulties.

Other genetic diseases include Tay - Sachs disease (damage to the gene for the enzyme hexosaminidase A leads to an accumulation of a chemical in the brain that destroys it), sickle cell anemia (improper coding of the gene that produces hemoglobin), hemophilia (lack of a gene for a blood - clotting factor) and muscular dystrophy (caused by a defective gene on the X chromosome).

Curis Inc. in Cambridge has received a $ 5.4 million, three - year grant from the Spinal Muscular Atrophy Foundation to identify therapeutic compounds to treat spinal muscular atrophy, a debilitating neuromuscular disease that is the leading genetic cause of infant and toddleMuscular Atrophy Foundation to identify therapeutic compounds to treat spinal muscular atrophy, a debilitating neuromuscular disease that is the leading genetic cause of infant and toddlemuscular atrophy, a debilitating neuromuscular disease that is the leading genetic cause of infant and toddler death.

Spinal muscular atrophy (SMA) is a juvenile autosomal recessive form of motor neuron disease caused by progressive degeneration of motor neurons in the spinal cord.

The condition is more common than muscular dystrophy and cystic fibrosis, but the development of new therapeutic concepts is hindered by the fact that unlike muscular dystrophy and cystic fibrosis, where a single mutated gene causing the disease is known, the entire human chromosome 21 (containing around 300 genes) still has to be dissected into individual gene - dose contributions to the DS symptoms.

About Spinal Muscular Atrophy Spinal Muscular Atrophy is a genetic, motor neuron disease caused by mutations in a single gene, SMN1.

The Spinal Muscular Atrophy Foundation awarded the grant to Curis to identify therapeutic compounds that could be used to treat the neuromuscular disease, which is the leading genetic cause of infant and toddler death.

Four years ago, researchers identified a genetic mutation associated with spinal muscular atrophy (SMA), an inherited neuromuscular disease that is the most common genetic cause of infant mortality...

SMA is a genetic, neuromuscular disease caused by progressive degeneration of nerve cells in the spinal cord that leads to muscular weakness and atrophy and increased risk for early death due to respiratory failure.

Spinal muscular atrophy (SMA) is a motor neuron disease and the leading genetic cause of death among infants and toddlers.

Caused by progressive degeneration of nerve cells in the spinal cord, the disease leads to increasing muscular weakness and atrophy.

The most common genetic killer of infants, a disease known as spinal muscular atrophy, is caused by mutations in a single gene.

According to this research, not only will it be possible to develop ways to improve muscular performance, but also explore causes of decreased muscular performance in a variety of diseases.

Fortunately, through physiological rewiring and neuromuscular re-education, eccentric isometrics help restore and repair the body's optimal physiology by addressing the root cause of disease and inflammation, namely muscular dysfunction.

Toxic heavy metals can cause, contribute to or accelerate the development of Alzheimer's disease, Parkinson's disease, muscular dystrophy, multiple sclerosis, and other brain and neurological disorders.13

Various disease such as muscular dystrophy and liver disease as well as age can cause a low creatinine level.

I have a Chronic Pain Disease, where I am missing a protein in my connective tissue which causes hypermobility and muscular knots.

Yes, he wants to put a face on the disease for researchers who have never met a child with Pompe, a type of muscular dystrophy in which glycogen build - up causes extensive muscular weakness, but that could cause, as Dr. Kent Webber (Jared Harris), a biotech VP with whom Crowley inevitably clashes heads, puts it, a lack of objectivity, maybe even causing scientists to cut corners.

One affects the bird's neurological system; one causes muscular disease and a third affects the bird's lungs and pulmonary system.

Chronic and progressive degeneration of muscular and ligamentous parts of the body due to any non infectious and congenital (inherited) disease can cause weakness in a dog's strength, where the mild stretching and pulling can lead to a sprain.

Many vets feel that the lack of these joints impairs the cat's balance and can cause weakness from muscular disease.

Muscular Dystrophies of Golden retrievers, German Short hair pointers and Rottweilers, Devon Rex and Sphynx cats are more of these genetically - based disease that can be the cause of high CK levels.

Vets treated acute and chronic wounds from dermatological diseases to muscular and skeletal issues caused by the heavy harnesses that they carry.