Sentences with phrase «mutant huntingtin interacting»

This abnormal binding causes more VCP accumulation on the mitochondria,» Nerve cells with VCP - mutant huntingtin interacting inside them became dysfunctional and self - destructed.

Not exact matches

Xin Qi, PhD, assistant professor of physiology and biophysics at Case Western Reserve University School of Medicine has been looking for proteins that interact with mutant huntingtin to better understand the initial steps of Huntington's disease progression.

The VCP inside mitochondria only interacted with mutant, but not healthy huntingtin protein.

The team identified the regions of VCP and mutant huntingtin that were interacting.

The researchers worked to identify ways to prevent VCP from heading to nerve cell mitochondria and interacting with mutant huntingtin protein once inside.