Sentences with phrase «mutant huntingtin produced»

Not exact matches

In March Chris Ross and his colleagues reported that cells bearing mutant huntingtin could survive if they produced extra CBP.

R6 / 2 mice have been genetically altered with an abnormal gene that makes them produce a harmful fragment of the mutant huntingtin protein

Note: these mice don't produce toxic mutant huntingtin protein.

When a person has too many CAGs in a row near the start of the huntingtin gene, a harmful «mutant» form of the protein is produced based on the instructions in the gene.

That's not what we expect when patients are given huntingtin - lowering drugs, which might produce around 50 - 75 % reductions in the mutant and healthy protein.