Sentences with phrase «mutated versions of those genes»

In contrast, blood cells from her parents, who each carried only one mutated version of the gene, produced healthy amounts of interferon when exposed to influenza.

Many children didn't carry mutated versions of those genes — but more than expected did.

In 2006, researchers discovered the genetic defect behind FOP: A mutated version of the gene ACVR1, which in patients produces an overactive form of a cell surface protein called a transmembrane receptor.

Not exact matches

The scientists are also experimenting with gene therapy, using a harmless virus to deliver a normal copy of the normal CIB2 gene to baby mice that have the mutated version.

People who inherit a mutated version of the ATF6 gene are born with a malformed or missing fovea, the eye region responsible for sharp, detailed vision.

The less adept mice, Rubin's team found, carry extra copies of a previously known human gene called DYRK; a mutated version of an almost identical gene in fruit flies, called minibrain, causes neurological defects.

To generate the models, Jackson created two mutated versions of the PrP - coding gene by changing a single codon — one of the three - nucleotide «words» in genes that code for the various amino acids in proteins.

When the researchers compared the mRNA to a library of DNA sequences taken from the dendrites of neurons by James Eberwine of the University of Pennsylvania Medical Center, they found that it came from a single gene on chromosome X — the human version of which, when mutated, leads to fragile - X syndrome.

In contrast, only 7 % to 15 % of newborns with mutated versions of either gene — or normal copies of both — were afflicted.

To determine the rate at which DNA mutates, researchers compare different versions of the same gene from two to several dozen species.

Upon sequencing the DNA, they found that DNA fragments containing mutated genes — markers of tumors — were typically smaller than healthy versions of the gene from within the same patient.

Scientists then looked at the human version of the gene, and found that the gene was mutated in people suffering from Native American myopathy.

While normal HD genes include up to 40 copies of the DNA sequence CAG, the mutated version is crammed with many more copies.

In two red - skinned varieties, however, they found only one version of the mutated gene; the other version worked just fine.

And researchers at Stanford University School of Medicine report in Genome Research that they linked the evolution of a gene in the old platypus to a mutated version in humans responsible for moving the testes outside of the body and into an external pouch, or scrotum.

The researchers found that in B cell tumors, mutated overactive versions of the Notch protein directly drive the expression of the Myc gene and many other genes that participate in B cell signaling pathways.

These mice have their hemoglobin genes removed and replaced with the mutated human version, saddling them with many of the same problems as human sufferers, including immature, short - lived, and sickle - shaped red blood cells; anemia; reduced blood flow; and an enlarged spleen.

The study team injected patients with a vector, a genetically engineered adeno - associated virus, which carried a normal version of a gene called RPE65 that is mutated in one form of LCA.

Using mutated versions of the lamin A gene as an example to demonstrate the versatility of their virus - based approach, researchers at the Salk Institute for Biological Studies successfully edited a diseased gene in patient - specific induced pluripotent stem cells as well as adult stem cells.

The researchers mutated the DNA of the killer germ to make many different versions of its genes.

In health, this gene helps to regulate DNA transcription, but a mutated version is found in many types of cancer cell, where it helps them to proliferate quickly.

Using mutated versions of the lamin A gene...

But, after researchers at Oregon Health and Science University managed to change the mutated version of the MYBPC3 gene to the unmutated version in a viable human embryo last month, the predictable bioethical debate was reignited, and terms such as «Designer Babies» got thrown around a lot.

And he's focusing on faulty (mutated) versions of a gene called JAK2.

To repair the problem, the research team «broke» the mutated version of the MYPBC3 gene inside human embryos, using technology that allows scientists to snip a specific target sequence on a mutant gene.

Results will indicate whether your dog has one, two, or no copies of the mutated version of the PRCD gene.