These mice have their hemoglobin genes removed and replaced with the
mutated human version, saddling them with many
of the same problems as human sufferers, including immature, short -
lived, and sickle -
shaped red blood cells; anemia; reduced blood flow; and an enlarged spleen.
There's a nefarious conspiracy here for audiences to unpack, and it's all part
of the way Peele uses a genre framework to explore how racism survives and
mutates in an All
Lives Matter culture, taking different insidious
shapes.