«This solves a long - running mystery of how a gene
mutation damages the neurons that carry information from the spinal cord to our muscles, resulting in a range of sensory and movement problems,» says Samuel Pfaff, a neuroscience professor at the Salk Institute and one of the senior authors on the paper with Xiang - Lei Yang, a professor at TSRI.
Not exact matches
ALD, for instance, is caused by
mutations in a gene called ABCD1, leading to unusually high levels of a type of fatty acid that
damages the material insulating some
neurons.
Mutations in tau cause neurodegeneration in human brains, and tau modified by the addition of phosphate groups (p - tau) forms aggregates and
damages neurons.