Sentences with phrase «mutational landscape»
The term "mutational landscape" refers to the overall picture or map of genetic changes or mutations that occur in an organism's DNA. It represents the various alterations in the genetic code that can happen, and how they might affect the organism's traits or characteristics. Full definition
Laddha SV, Ganesan S, Chan CS, White E. Mutational landscape of the essential autophagy gene BECN1 in human cancers.
cinj.org
Various genomic structures and epigenetic states are known to shape and modify mutational landscapes across genomes [64].
Through the project, researchers analyze the mutational landscape of each patient's tumor and suggest clinical trials or approved drugs that might be appropriate for that patient, according to Chinnaiyan.
The study describes the mutational landscape of bladder cancer cell lines.
However, a number of genes linked to neuropsychiatric diseases have no assigned function, and it is likely that the mutational landscape of these diseases will be complexified by the wealth of data generated with next generation sequencing techniques.
An international research team, including four Simon Fraser University scientists, has identified the «mutational landscape» of intrahepatic cholangiocarcinoma (ICC), a rare, highly fatal form of liver cancer that disproportionately...
So what was the mutational landscape of luminal - type breast cancer?
Our laboratory recently developed an interest in circulating tumor DNA (ctDNA), which may be used to determine the mutational landscape of a given tumor.
The afternoon of the second day focused on somatic changes in melanoma, that is changes that occur in the tumour itself, and this session saw talks from ESR07 Sofia Chen on the mutational landscape of primary melanoma tumours; ESR08 Catarina Salgado on DNA hydroxymethylation (a form of regulation) in melanoma and naevi; and ESR10 Adriana Sanna on epigenetic regulation (reversible changes to the DNA which can turn genes on / off) of melanoma cell phenotypes.
In most genetic diseases, the mutational landscape is broad and varied, necessitating the development of many distinct CRISPR therapies to match these different mutations.
In this way, the mutational landscape of autophagy genes in human cancers can be more precisely defined.
Radiocarbon, an international journal of radiocarbon and other isotope dating In a study of the mutational landscape of p53 - immunopositive patches (PIPs), which may represent early squamous cell carcinoma precursors in the skin