Sentences with phrase «mutations in a large sample»

The hypothesis took hold in 2007, when a team from the University of Tartu in Estonia identified a set of mutations in a large sample of Native American mitochondrial DNA.

Not exact matches

To identify the relevant mutations the scientists analyzed the blood samples of 1,858 men from three independent cohorts in Europe and North America: the Swiss arm of the European Randomized Study for Prostate Cancer Screening, the large American Screening trial, Prostate, Lung, Colorectal, and Ovarian (PLCO), Princess Margaret Cancer Centre (University Health Network) and Mount Sinai Hospital (Sinai Health System) in Toronto.

Seven tumors, he says, is not a large enough sample to see the entire spectrum of mutations in prostate cancer.

The authors conclude that «re-sequencing in large samples of phenotypically extreme individuals, on the other hand, is much more likely to discover rare, large - effect mutations that are predicted... to be deleterious.»

The first manuscript entitled, Circulating Free Tumor - derived DNA (ctDNA) Determination of EGFR Mutation Status in Real - World European and Japanese Patients with Advanced NSCLC: the ASSESS Study, used samples from the large ASSESS study to evaluate EGFR mutation status by analyzing ctDNA from bloodMutation Status in Real - World European and Japanese Patients with Advanced NSCLC: the ASSESS Study, used samples from the large ASSESS study to evaluate EGFR mutation status by analyzing ctDNA from bloodmutation status by analyzing ctDNA from blood plasma.

So far this mutation has been detected in this breed only, with an estimated carrier frequency of 25 % based on a large number of samples collected form dogs originated from Finland, Sweden, United Kingdom and United States.