Sentences with phrase «mutations in a variety of cancers»

Despite the prevalence of Ras mutations in a variety of cancers, Ras proteins have stumped the pharmaceutical industry for years.

Not exact matches

Large - scale cancer sequencing efforts such as TCGA and ICGC have catalogued somatic mutations in a variety of common cancer types.

COSMIC, the «Catalogue Of Somatic Mutations In Cancer» is an expert - curated database encompassing the wide variety of somatic mutation mechanisms causing human canceOf Somatic Mutations In Cancer» is an expert - curated database encompassing the wide variety of somatic mutation mechanisms causing human cCancer» is an expert - curated database encompassing the wide variety of somatic mutation mechanisms causing human canceof somatic mutation mechanisms causing human cancercancer.

Their research found that a variety of naturally - occurring mutations in the DNA cells can initiate different sequences of mutations that eventually lead to breast cancer.

We also have research interests in cellular regulation by ADP - ribosylation, which links epigenetics to metabolism; lipid kinases; and sphingolipid biosynthesis, which has strong links to both inflammation and cancer, and where mutations in the various proteins involved are associated with a variety of rare diseases.

These findings sparked a wave of discovery in cancer research, and uncovered 20,000 distinct mutations of TP53 in a variety of human cancers.