The word
"mycobacterial" refers to a type of bacterium called mycobacteria. These bacteria can cause diseases such as tuberculosis and leprosy in humans and animals.
Full definition
The protein — which is not known to exist in other rod - shaped bacteria or other organisms — seems to allow for asymmetrical growth in new
mycobacterial cells made during cell division.
The latest study establishes that a closely related protein apparatus called Ligase C, whose function was unclear until now, combines with other repair proteins to fix damaged DNA bases
in mycobacterial genomes caused by the attack of oxygen free radicals.
As more
mycobacterial genomes are sequenced, a picture is emerging that Distributive Conjugal Transfer may have shuffled the genomes of environmental mycobacteria to create a strain that was particularly well suited for growth in mammalian lungs.
Since 18 years, the research focus of the MyTb lab is to characterise and understand human immune responses to Mycobacterium tuberculosis with emphasis on
mycobacterial lipids.
Thus, scientists may have to re-evaluate the projected time it might take for a
new mycobacterial strain to evolve, suggest the authors.
As a result, blood tests may be detecting the presence of
other mycobacterial infections; they may also produce false positives when antibody levels remain elevated after cases of TB have been treated.
Cats can also develop nodules on the skin of their abdomen
from mycobacterial infections, which are caused by organisms commonly found in soil and water.
Informations on meetings related to tuberculosis or
nontuberculous mycobacterial infections and on our TBnet meetings are provided under this link.
Identifying and characterizing
mycobacterial factors required for survival and virulence in cellular models of infection, with a particular focus on virulence lipids.
In addition, the department is focusing on the study of the mechanisms for the differentiation of immune cells
by mycobacterial virulence factors to develop the effective control tools of M. tuberculosis infection.
The protein may be a target for intervention; blocking it might result in
less mycobacterial diversity and shorten TB treatment courses.
The mechanisms underlying this ability and the extent to which the cells» size, growth rate and other physiological properties relate to survival in
mycobacterial populations were not well understood.
Her laboratory is accredited to ISO / IEC 17025 and is responsible for EU batch release and standardisation of
mycobacterial products, such as Lyophilised BCG.
Gilleron M *, Stenger S *, Mazorra Z, Wittke F, Mariotti S, Böhmer G, Mori L, Puzo G, DeLibero G. Diacylated sulfoglycolipids are
novel mycobacterial antigens stimulating CD1 - restricted T cells during infection with Mycobacterium tuberculosis.
His research focuses on the identification and validation of
mycobacterial proteins as drug targets, and elucidating mechanism of action of drugs active against Mycobacteria.
Publications Dr. Riggs» chapter on
Avian Mycobacterial Disease will be included in the upcoming Zoo and Wild Animal Medicine: Current Therapy by Fowler and Miller
Informations on meetings related to tuberculosis or
nontuberculous mycobacterial infections and on our NTM - NET meetings are provided under this link.
«We have shown that by removing LigC and D,
mycobacterial cells become much more sensitive to oxidative damage.
The team also exploited a genomic mapping approach similar to those applied in sexually reproducing organisms to localize
the mycobacterial genes that determine mating identity.
Of the nearly 7,000 genes in
the mycobacterial genome, one region spanning just 6 genes appears to be key in determining whether a mycobacterial strain will be a donor or recipient when it comes to mating.
Tuberculosis bacteria belong to
the mycobacterial pathogens.
Dr Luiz Pedro Carvalho, from
the Mycobacterial Metabolism and Antibiotic Research Laboratory at the Francis Crick Institute, said:
By maintaining a careful balance between fermentation and respiration,
the mycobacterial cell can remain energised and unstressed.
How
a mycobacterial lipid subverts host macrophages in tuberculosis and leprosy Lalita Ramakrishnan University of Cambridge, UK 20th October 201704:15 pm Host: Pedro Alves, MPIIB Location: Max Planck Institute for Infection Biology, Seminar room 1 +2 - Campus Charité Mitte
In addition, analysis of Biobank genotype resources indicated that people carrying this mutation were healthy, and no more susceptible to
mycobacterial, bacterial, viral, or fungal infection.
The Dockrell laboratory is also using
the mycobacterial growth inhibition assay in BCG - vaccinated infants and patients with latent TB infection and helminth infection.
Mycobacterium tuberculosis (Mtb) DprE1, an essential isomerase for the biosynthesis of
the mycobacterial cell wall, is a validated target for tuberculosis (TB) drug development.
The cause of this isn't always clear, but could be genetic or the result of trauma, calcium deficiency, or
a mycobacterial infection.
Many cats which have
Mycobacterial infections have spontaneously - resolving...
Male cats (n = 12) were divided into groups of three and were immunized once with 0 (sham), 50, 200, or 400 microg synthetic GnRH coupled to keyhole limpet hemocyanin and combined with
a mycobacterial adjuvant to enhance immunogenicity.
Vaccinated cats (n = 15) received a single injection of vaccine containing a GnRH - KLH conjugate (200 μg) emulsified in
a mycobacterial and oil adjuvant on study Day 0.
Phrases with «mycobacterial»