Sentences with phrase «mycoides cells»

We report the design, synthesis, and assembly of the 1.08 — mega — base pair Mycoplasma mycoides JCVI - syn 1.0 genome starting from digitized genome sequence information and its transplantation into a M. capricolum recipient cell to create new M. mycoides cells that are controlled only by the synthetic chromosome.

The transplanted genome booted up in its host cell, and then divided over and over to make billions of M. mycoides cells.

We cloned a Mycoplasma mycoides genome as a yeast centromeric plasmid and then transplanted it into Mycoplasma capricolum to produce a viable M. mycoides cell.

Not exact matches

The cell was created by stitching together the genome of a goat pathogen called Mycoplasma mycoides from smaller stretches of DNA synthesised in the lab, and inserting the genome into the empty cytoplasm of a related bacterium.

Only those cells that absorbed the M. mycoides genome survived.

The researchers worked with Mycoplasma mycoides (a microbe that infects goats) because it has one of the smallest genetic blueprints of any known self - replicating organism and lacks cell walls, making it easier to insert new DNA.

These cells that result from genome transplantation are phenotypically identical to the M. mycoides LC donor strain as judged by several criteria.

Intact genomic DNA from Mycoplasma mycoides large colony (LC), virtually free of protein, was transplanted into Mycoplasma capricolum cells by polyethylene glycol — mediated transformation.

A synthetic Mycoplasma mycoides genome transplanted into M. capricolum was able to control the host cell.

The team, who published some of their first studies as early as 1999, culminated their efforts with the first synthetic cell, Mycoplasma mycoides JCVI - syn 1.0 in 2010, and in March 2016 published result of the successful construction of the first minimal synthetic cell, JCVI - syn 3.0.