Sentences with phrase «mycoplasma genomes»

The researchers identified 782 genes, the highest number among the four mycoplasma genomes sequenced to date.

Although the genome of M. pulmonis is the largest of the four sequenced mycoplasma genomes, the researchers were surprised to find that «several of the genes previously reported to be essential for a self - replicating minimal cell are missing in the M. pulmonis genome.»

Today the scientists are figuring out how to cement dozens of those 5,000 - letter - size chunks into a single piece of DNA big enough to hold an entire Mycoplasma genome.

The scientists also used the Hi - C technique to study more detailed patterns of organisation within the Mycoplasma genome.

We had suspected that the Mycoplasma genome might have a similar overall organisation to other bacteria, but we were completely surprised to find that it was also organised into domains, which can be considered as regulatory units of chromatin organisation and that we had identified a previously unknown layer of gene regulation.

Not exact matches

All what the the researchers transplanted an entire natural genome - the genetic code - of one bacterium into another and watched it take over, turning a goat germ into a cattle germ.The researchers picked two species of a simple germ named Mycoplasma.

In a work published in the online version of Science magazine in May 2010, whose authors were Daniel Gibson et al., they describe the synthetic assembly of the genome needed to create the bacterium Mycoplasma mycoides.

But this June, he and his colleagues delicately teased out the entire genome of Mycoplasma mycoides (which infects goats) and slipped it into Mycoplasma capricolum, a related but distinctly separate species.

To build the minimal genome, Venter turned to a microbe he and his colleagues had already been studying for several years, a pathogen known as Mycoplasma genitalium that causes urinary tract infections.

Venter's team, based at the J. Craig Venter Institute in Rockville, Maryland, took the genome of one bacterium, Mycoplasma mycoides, copied it and transferred it to yeast for easier modification, and then implanted it into another bacterial species, Mycoplasma capricolum.

We have synthesized a 582,970 — base pair Mycoplasma genitalium genome.

The cell was created by stitching together the genome of a goat pathogen called Mycoplasma mycoides from smaller stretches of DNA synthesised in the lab, and inserting the genome into the empty cytoplasm of a related bacterium.

Venter's team took the genome of one bacterium, Mycoplasma mycoides, copied and modified it in yeast, and then transplanted it into another bacterial species, M. capricolum.

We cloned a Mycoplasma mycoides genome as a yeast centromeric plasmid and then transplanted it into Mycoplasma capricolum to produce a viable M. mycoides cell.

In a 1995 Science paper, Venter's team sequenced the genome of Mycoplasma genitalium, a sexually transmitted microbe with the smallest genome of any known free - living organism, and mapped its 470 genes.

In January scientists at the J. Craig Venter Institute in Rockville, Md., reported making all 582,970 base pairs that constitute the genome of the bacterium Mycoplasma genitalium.

The newly - created bacterium contains a minimalist version of the genome of Mycoplasma mycoides.

Mycoplasma already have some of the smallest known genomes.

Last August you reported cloning the entire genome of a bacterium, Mycoplasma mycoides.

The synthetic genome was modeled after that of a tiny bacterium called Mycoplasma genitalium, carrying all the same genes in roughly the same order.

For most of the last 40 years, scientists thought the smallest genomes belonged to bacteria of the Mycoplasma genus.

Ever since his group decoded the genome of Mycoplasma genitalium, a parasitic bacterium that lives in the human urogenital tract, sequencing maverick J. Craig Venter has wanted to remake the bug's genome in the lab.

A synthetic Mycoplasma mycoides genome transplanted into M. capricolum was able to control the host cell.

We report the design, synthesis, and assembly of the 1.08 — mega — base pair Mycoplasma mycoides JCVI - syn 1.0 genome starting from digitized genome sequence information and its transplantation into a M. capricolum recipient cell to create new M. mycoides cells that are controlled only by the synthetic chromosome.

Working together with colleagues in Spain, Japan and Australia, researchers led by Luis Serrano, ICREA research professor and leader of the Design of Biological Systems laboratory at the Centre for Genomic Regulation, focused their attention on the organisation of DNA within an organism with an extremely small genome — the pneumonia pathogen Mycoplasma pneumoniae.

However, it was thought that these domains would not be found in Mycoplasma, because its genome is so small and it only makes around 20 different DNA binding proteins responsible for organising the chromosome, compared to the hundreds made by other bacterial species.

On sabbatical leave in Ellson Chen's lab at Applied Biosystems, Inc. (1995 - 1997) he sequenced the genome of Ureaplasma parvum and began his study of mycoplasma genomics.

It is the third mycoplasma to be sequenced, and has the smallest sequenced prokaryotic genome except for M. genitalium.

Researchers have sequenced the genome of Mycoplasma pulmonis, a microscopic bacterium that causes respiratory and genital infections in mice and rats.