Sentences with word «myelination»

Skin stimulation speeds the process of myelination of the brain and nervous system hence it improves brain - body communication.

«In the case of multiple sclerosis, as a patient progresses through steps of the disease, their body generates novel antibodies or higher existing antibody titers against certain proteins, such as myelination proteins.

At the two - month mark, something major has happened: your baby's brain stem has started communicating with his cerebral cortex, a process called myelination.

Sidoli M, Musner N, Silvestri N, Ungaro D, D'Antonio M, Cavener DR, Feltri ML, Wrabetz L. Ablation of perk in schwann cells improves myelination in the S63del Charcot - Marie - Tooth 1B mouse.

«Our findings provide direct evidence that B cells reside in the mouse neonatal brain and promote both oligodendrocyte proliferation and neuron myelination.

I think part of the concern is that more and more studies are or some studies at least have shown that there is subtle accommodative deficits that they may have later in adulthood, problems of nerve myelination, kids performing lower on certain development skills, cognition, concentration, just more subtle things that are very hard to quantify.

This also occurs in babies under c. 1 year, because of low myelination of the corticospinal tracts.

- Stimulation of the skin speeds myelination of the nervous system.

«But it's not simply a temporary defect that only results in delayed myelination.

«Because we found changes in the brain as a consequence of binge eating that were predictive of decreased myelination, therapeutically promoting remyelination may represent a novel treatment avenue for promoting recovery from negative feeding behaviors in eating disorders,» explained corresponding author Camron Bryant, PhD, assistant professor of Pharmacology and Experimental Therapeutics & Psychiatry at BUSM.

A key discovery from her group in recent years was the finding that Contactin - 1 is required for myelination in the central nervous system.

Radial axonal growth initiates with myelination, and is dependent upon the C terminus of neurofilament medium (NF - M).

Professor Declan Murphy, Institute of Psychiatry at King's, who oversaw the research, said: «Until now, we've not been able to show how myelination develops in babies but this new MRI technique allows us to do just that.

Neuroscientists at UCLA, who have studied myelination in the brains of adults ages 23 to 80, reported in September that the coating peaks around age 39 — the same age at which participants hit top speeds in standard tests of motor abilities.

Myelination refers to the process of making myelin, a fatty sheath that surrounds and insulates nerve fibers so that they can carry information.

They are lost as the pyramidal tracts gain functionality with progressive myelination.

Myelination begins in utero when a fetus is about 16 weeks and continues into adulthood.

In very young children, messages move more slowly in the brain, since myelination is not yet complete.

The team discovered that the B immune cells, called B - 1a cells, ensure that enough of these oligodendrocytes are available in the developing brain to support adequate myelination.

Treated mice retained several times more myelination and oligodendrocytes than untreated mice.

«We looked at the optic nerve and saw normal myelination,» Mukherjee said, referring to the fatty white sheathing wrapped around axons, the nerve fibers that allow information transmission over distances to proceed efficiently and rapidly.

The team found that this enzyme is essential for the correct composition of lipids in the insulating layers, for the cells to start myelination, and for the healthy growth of myelin layers.

«Knowing how reduced lipid synthesis affects myelination during development is an important step towards gaining a better understanding of how these kinds of diseases progress,» she says.

Buchsbaum theorizes that myelination mishaps lead to «misrouting of messages» in the brain that could account for both the cognitive disarray of schizophrenia and mood swings of bipolar illness.

For example, a gene called PLP1, which produces the most abundant myelination - related protein, was about 60 % less active in the schizophrenics and 70 % less active in manic depressives, compared with controls.

WMI has adapted an immune tolerance — like mechanism whereby persistent engagement of TLR4 by bHAf promotes an OPC niche at the expense of myelination by engaging a FoxO3 signaling pathway that chronically constrains OPC differentiation.

Musner N, Sidoli M, Zambroni D, Del Carro U, Ungaro D, Ron D, D'Antonio M, Feltri ML and Wrabetz L. Perk ablation ameliorates myelination in a Charcot - Marie - Tooth 1B neuropathy mouse model.

We identified a specific bioactive hyaluronan fragment (bHAf) that downregulates myelin gene expression and chronically blocks OPC maturation and myelination via a tolerance - like mechanism that dysregulates pro-myelination signaling via AKT.

Resetting translational homeostasis restores myelination in CMT1B mice.

Sox2 expression in Schwann cells inhibits myelination in vivo and induces influx of macrophages to the nerve.

Her research focuses on the characterization of potential mechanisms behind bioenergetic and myelination abnormalities seen in a number of psychiatric conditions and how they may be disrupted by disease.

Gage has also developed an in vitro myelination model using iPSCs to be used for screening of pharmacological compounds and to better understand diseases such as schizophrenia and Parkinson's.

Starting with transplants of human oligodendrocytes in the late 1980s [40], and more recently with populations of human oligodendrocyte progenitor cells isolated from the developing or adult CNS, or from human embryonic stem cells, it has been possible to generate extensive myelination upon transplantation into spinal cord injury or into congenital mouse models of hypomyelination [41]--[48].

The most common form affects infants and young children, and is characterized by progressive failure of central myelination, usually leading to death usually within the first decade.

Myelination transition zone astrocytes are constitutively phagocytic and have synuclein dependent reactivity in glaucoma.

Individuals with CMT1 typically show signs of abnormal myelination.

Long term memories are formed by moving information stored in the short term memory the previous day to the long term memory and myelination happens mostly during sleep as well where the fat or insulation is laid down on the neuropathways which integrates all these new experiences in the brain.

As mentioned above, vitamin B12 deficiency results in restricted myelination, and depending on the area of the nervous system affected, the child can present with varied cognitive and intellectual problems.

Myelination enables nerve fibers to transmit signals quickly — without it, brain cells just don't communicate that well.

Interesting to note, one of the last places myelination occurs is in the brain's frontal lobe, which is responsible for decision making and sound logic.

Because coconut oil supports thyroid function, and thyroid governs brain development, including myelination, the result might simply reflect the difference between normal and hypothyroid individuals.

Iodine is especially important for fetal brain development and proper myelination of the central nervous system.

«It could be smaller, or have reduced myelination, meaning it's less fast, or it could have more crossing fibers, meaning there's more «traffic lights,»» explains Gaab.

Creating new neurological pathways, through deliberate active thinking and participation, not only has the potential to create a new brain map; it also has the potential to lead to added axonal myelination.

The literature contains a report of genetically modified mice that do not express this gene that show decreased growth, generalized tremor, ataxia, impaired CNS myelination, and decreased survival.