Sentences with word «myeloablative»

Allogeneic Sibling Donor Peripheral Blood Stem Cells Transplantation With Myeloablative Conditioning for Chronic Myeloid Leukemia in Blast Crisis - Successful Treatment Despite Severe Phase of the Disease

The study on allogeneic SCT with reduced - intensity conditioning in comparison with allogeneic SCT with myeloablative conditioning, which was now additionally available, had no effect on the assessment: Due to its overall low certainty of results, neither an advantage nor a disadvantage of the two treatment variants could be derived from the data.

In a previous study by the same group 78, autologous culture - expanded MSC were infused to breast cancer patients to investigate whether MSC would enhance the engraftment of peripheral blood stem cells after myeloablative therapy.

Along the way, we became interested in using cord blood as an alternative donor source for hematopoietic reconstitution after myeloablative therapy.

While it has been studied that cognitive impairment after myeloablative allogeneic BMT can occur, it has been unclear if similar impacts to cognitive functioning occurs after reduced - intensity allogeneic or after autologous BMT.

However, even though these patients don't have a blood problem, vis a vis these diseases typically affect brain, heart, and or other organs, they have to undergo myeloablative chemotherapy so their body doesn't reject the donor cells.

In regards to the optimal conditioning regimen, myeloablative conditioning (MAC) was associated with a higher 3 - year disease - free survival versus a reduced intensity conditioning (RIC) regimen [12].

A combination of our current protocol with a myeloablative treatment approach might further improve HPC engraftment in immunocompetent mice.