Sentences with word «myeloperoxidase»

The researchers also found that Splenda ingestion results in increased myeloperoxidase activity in the intestines of mice with the bowel disease, but not in the healthy mice.
The findings suggest that consumption of Splenda may increase myeloperoxidase production only in individuals with a pro-inflammatory predisposition, such as Crohn's disease or other forms of inflammatory bowel disease patients.
Based on the results of immunohistochemical analysis, the cells are TdT (+), CD56 (+), CD123 (+) and negative for myeloperoxidase (MPO), CD34, CD117, CD20, CD3 and EBV.
A given rise of [Ca2 +] i elicited by the chemotactic peptide formylmethionylleucylphenylalanine (FMLP) was associated with a much greater degree of superoxide generation and myeloperoxidase secretion than was the same or larger [Ca2 +] i produced by a specific calcium ionophore, ionomycin, which bypasses cell surface receptors.
This could include unexpected foodborne bacterial infections which would further recruit myeloperoxidase - containing leukocytes to the intestinal tract and the resultant inflammation.»
Human myeloperoxidase: a potential target for molecular MR imaging in atherosclerosis.
Four hours after the meal, measures of artery function, red blood cell appearance, and the levels of an enzyme called myeloperoxidase or MPO (which is capable of damaging arteries) were all measured.
Proficient in specialized stains including the Wright Stain, Prussian Blue Stain, Kleihauer - Betke Stain, Myeloperoxidase Stain, and Oil Red O Stain.
Progesterone significantly reduces infarct area, lipid peroxidation levels and activity of myeloperoxidase in myocardial ischemia / reperfusion injury.
The inference is that the increased presence of E. coli intensified the myeloperoxidase activity in the bowel as the body sought to fight off the invader.
In addition to illustrating the experimental role of a sucralose - maltodextrin based artificial sweetener in promoting intestinal dysbiosis [a microbial imbalance] and myeloperoxidase activity, the studies indicate that it might be possible to measure Proteobacteria and myeloperoxidase as simultaneous fecal biomarkers in patients to monitor their gut (disease / health) adjustment to their diets.
Myeloperoxidase is an enzyme in leukocytes (white blood cells) that is effective in killing various microorganisms.
These children experienced significant improvements in four measures: weight, waist circumference, mid-arm circumference and myeloperoxidase.
These children experienced significant improvements in nine measures: BMI, systolic blood pressure, weight, mid-arm circumference, total cholesterol, low - density lipoprotein (LDL) cholesterol, and insulin, as well as two common markers of heart disease, myeloperoxidase and high - sensitivity C - reactive protein.
Research Interests: inflammation; atherosclerosis; asthma; myeloperoxidase; cardiovascular diseases; HDL; peroxidases; airway remodeling; intestinal microbiota; gut flora; cardiometabolic disease
The results of this trial demonstrate that DG031 not only effectively supresses the synthesis of leukotriene B4, but at the same time also reduces levels of myeloperoxidase, another marker correlated with cardiovascular risk,» said Dr. Kari Stefansson, CEO of deCODE.
One centers on the role of myeloperoxidase, a protein found in white blood cells that plays an important role in fighting infections, but which we have discovered also participates in development of heart diseases.
• Study achieves primary endpoints; DG031 shown to be well - tolerated and to significantly reduce levels of leukotriene B4 and myeloperoxidase • First ever clinical trial based upon the isolation of a disease gene in a common disease
One research program focuses on the role of myeloperoxidase, a leukocyte heme protein, in promoting oxidant stress in vivo, and its participation in cardiovascular diseases.
At the highest dose level, DG031 reduced levels of myeloperoxidase (MPO), higher levels of which have been linked to increased risk of heart attack.
• Study achieves primary endpoints; DG031 shown to be well - tolerated and to significantly reduce levels of leukotriene B4 and myeloperoxidase • First ever clinical trial based upon the isolation of a disease gene in a common disease Reykjavik, ICELAND, October 19,...
Paulsen G, Egner I, Raastad T, Reinholt F, Owe S, Lauritzen F, Brorson SH, Koskinen S Inflammatory markers CD11b, CD16, CD66b, CD68, myeloperoxidase and neutrophil elastase in eccentric exercised human skeletal muscles Histochem Cell Biol (in press) PubMed 23224298
You might look up the myeloperoxidase pathway.
The immune defense against these infections is glucose - dependent (as it relies on production of reactive oxygen species using glucose) and thyroid hormone - dependent (as thyroid hormone drives not only glucose availability, but also the availability of iodine for the myeloperoxidase pathway).
Parameters of antioxidant defense and oxidative damage, myeloperoxidase, several cytokines, fecal calprotectin and CRP were determined.
Histological (villus height, crypt depth (CD) and disease severity score) and biochemical (myeloperoxidase (MPO) activity) parameters were determined in intestinal tissues collected at sacrifice.
These types of free radicals are mainly produced by cellular enzymes such as NADPH - oxidase, myeloperoxidase and nitric oxide synthase (NOS).
Myeloperoxidase and High - Sensitivity C - Reactive Protein for Predicting Major Adverse Cardiovascular Events in Patients with Coronary Heart Disease
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